A Case of Vaginal Cancer with Uterine Prolapse

Kim, Hwi-Gon; Song, Yong Jung; Na, Yong Jin; Choi, Ook-Hwan

doi:10.6118/jmm.2013.19.3.139

Cited by 10 publications

(16 citation statements)

References 9 publications

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“…Rarely, as seen in our patient, due to chronic irritation, primary vaginal cancer may develop secondary to prolonged POP. However, primary vaginal or cervical cancer and POP combination is rarely reported in the literature [4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19]. The increase in the incidence of both POP and primary vaginal cancer with advancing age makes this combination more frequent in elderly people [1].…”

Section: Discussionmentioning

confidence: 99%

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Using a pessary during radiotherapy in reducible pelvic organ prolapse and vaginal cancer: a case report and review of the literature

Gültekin

Esen

Akgör

et al. 2020

jcb

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Purpose: Primary vaginal cancer and pelvic organ prolapse (POP) combination is extremely rare. Although definitive chemoradiotherapy (CRT) and brachytherapy (BT) is the standard treatment for advanced stage primary vaginal cancer, there is a limited data about the treatment of primary vaginal cancer combined with POP due to its rarity. In addition, radiotherapy (RT) process may be difficult in these cases and often result in more toxicity. Case presentation: In this case report, we present a 77-year-old woman with a diagnosis of primary vaginal cancer associated with POP, who was treated with definitive CRT using a pessary to restore vaginal anatomy for optimal radiation. Following CRT, complete response was observed and vaginal cuff BT was performed. The patient tolerated the treatment very well and is still alive without disease at 10-months follow-up. Conclusions: Combined primary vaginal cancer and POP is an extremely rare clinical entity, with only a few cases reported in the literature. When applying CRT in these cases, critical organ doses may be higher than expected due to the downward descent of the pelvic organs. Especially in elderly patients, a pessary can be used as a non-surgical procedure to restore the anatomy for symptom relief during definitive CRT. Additionally, it allows tumors to be targeted more precisely.

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Section: Discussionmentioning

confidence: 99%

“…Vaginal trauma, chronic irritation, and inflammation of the vaginal mucosa can cause primary vaginal cancer in patients with POP [3]. However, a combination of POP and primary vaginal or cervical cancer is an extremely rare entity [4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19].…”

Section: Purposementioning

confidence: 99%

Using a pessary during radiotherapy in reducible pelvic organ prolapse and vaginal cancer: a case report and review of the literature

Gültekin

Esen

Akgör

et al. 2020

jcb

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“…Primary carcinoma of the vagina is rare and association with third-degree uterovaginal (UV) prolapse is even rarer, constituting 1%–2%[1] of all gynecologic malignancies. Incidence peaks in 6 th and 7 th decade of life.…”

Section: Introductionmentioning

confidence: 99%

Vaginal carcinoma with third-degree uterine prolapse

Sheikh

Date

Darekar

2019

Int J App Basic Med Res

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Carcinoma of vagina in a case of uterovaginal (UV) prolapse is very rare. We hereby present a case of 72-year-old woman with uterine prolapse with ulcerative growth of 4 cm × 2 cm on vagina commonly considered as decubitus ulcer. However, for confirmation, punch biopsy was performed, which confirmed it as vaginal carcinoma. The patient underwent vaginal hysterectomy with colpoperineorrhaphy with wide excision of tumor margin and received radiotherapy postoperatively. This case illustrates the importance of biopsy of an ulcer in cases of UV prolapse to rule out malignancy to avoid incomplete treatment.

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“…Some authors report the metastases of vaginal cancer coexisting with prolapse to the chest, nodes, liver, iliac bone. [ 3 , 4 ]…”

Section: Introductionmentioning

confidence: 99%

Primary vaginal squamous cell carcinoma with bladder involvement in uterine prolapsed patient

Fedus¹,

Raś²,

Książek

et al. 2017

Medicine

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Rationale:Primary vaginal squamous cell carcinoma (SCC) is a rare disease. Primary SCC in prolapsed vagina is extremely rare. In the presented case additional bladder involvement was found.Patients concerns:Primary vaginal SCC may be misinterpreted as decubitus in prolapsed vagina and it may delay proper diagnosis and treatment.Diagnoses:Diagnosis was confirmed by the vaginal ulceration biopsy and cystoscopic biopsy of the involved bladder.Interventions:In the case presented percutaneous nephrostomy was the only possible treatment of hydronephrosis.Outcomes:In advanced primary SCC (Figo IVA) with nodal involvement palliative treatment is only option.Lessons:Primary SCC mimicking decubitus which appeared in prolapsed vagina, may be accompanied by bladder involvement.

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A Case of Vaginal Cancer with Uterine Prolapse

Cited by 10 publications

References 9 publications

Using a pessary during radiotherapy in reducible pelvic organ prolapse and vaginal cancer: a case report and review of the literature

Using a pessary during radiotherapy in reducible pelvic organ prolapse and vaginal cancer: a case report and review of the literature

Vaginal carcinoma with third-degree uterine prolapse

Primary vaginal squamous cell carcinoma with bladder involvement in uterine prolapsed patient

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