A case report and review of lymphocutaneous nocardiosis caused by
            <i>Nocardia brasiliensis</i>
            reported in China

Mu, Yunzhu; Liu, Ying‐; Wang, Yu‐Juan; Zhang, Zhengzhong

doi:10.1111/dth.13001

Cited by 9 publications

(1 citation statement)

References 21 publications

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“…One was reported by Chu et al 10 in 2017 and occurred in an 87-year-old woman following a wasp sting. Another case was reported by Zhang et al 11 in 2019 and occurred in a 42-year-old woman following an unknown insect bite. In this present case, the patient was finally diagnosed with the lymphocutaneous type of primary cutaneous nocardiosis caused by N. brasiliensis.…”

Section: Discussionmentioning

confidence: 88%

Lymphocutaneous nocardiosis caused by Nocardia brasiliensis in an immunocompetent patient: a case report

et al. 2020

J Int Med Res

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Nocardia usually manifests as opportunistic infections in immunocompromised hosts. Here, we report a rare case of an immunocompetent patient with lymphocutaneous nocardiosis. The patient was a 34-year-old man presenting with fever, multiple scattered pustules on both upper limbs and several subcutaneous nodules on the left elbow and forearm. Skin biopsy of the subcutaneous nodule revealed suppurative inflammation of the lymph nodes. Pus cultures were finally identified as Nocardia brasiliensis. The patient fully recovered without relapse after receiving optimized antimicrobial therapy consisting of linezolid combined with sulfonamides. Nocardiosis is a rare opportunistic disease which may be fatal and usually affects immunocompromised hosts, resulting in suppurative and granulomatous inflammation. Nocardia has a long culture cycle, is difficult to diagnose, and is more likely to be neglected in healthy young people. The present case suggests that physicians should be aware that nocardiosis is a differential diagnosis to consider in patients with suppurative infection, especially when anti-infective treatment is ineffective.

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Section: Discussionmentioning

confidence: 88%