A Case Report of a Patient with Probable-REM Sleep Behavior Disorder Treated by <italic>Ukgan-san</italic> with Western Medicine

Abstract

Objectives: This study examined the case of a 69-year-old man with a history of stroke and Alzheimer’s disease who had been diagnosed with probable-rapid eye movement sleep behavior disorder (probable-RBD).Methods: The patient was treated with herbal medicine (&lt;i&gt;Ukgan-san, Ukgansangayonggolmoryeo-tang&lt;/i&gt;, and powdered &lt;i&gt;Gamisoyo-san&lt;/i&gt; extract), Western medicine (clonazepam, antiplatelet, psychotropic agents, antihypertensive drugs, and others), and acupuncture. Their effects were evaluated by the frequency and severity of sleep-related behavioral symptoms.Results: After treatment, the observed frequency and severity of sleep-related behavior decreased.Conclusion: The results suggest that using traditional Korean medicine with clonazepam can be effective in the treatment of patients with probable-RBD.