A case report of a clinically diagnosed advanced lung cancer patient after treatment with Gunchilgyebok-Jung

Park, So jung; Kang, Hwi joong; Park, Ji hye; Cho, Chong kwan; Yoo, Hwa Seung

doi:10.15432/jkto.2015.20.1.023

Cited by 3 publications

(1 citation statement)

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“…Previous research reported that Rhus verniciflua Stokes had therapeutic effects in patients with NSCLC, in that it prolonged survival time and was well tolerated [ 10 ]. Park et al [ 11 ] reported that geonchilgyebok- jeong treatment had considerable anti-tumor effect and immunopotentiating activity, without adverse effects, in patients with lung cancer.…”

Section: Discussionmentioning

confidence: 99%

Combination Therapy of Gefitinib and Korean Herbal Medicines Could be a Beneficial Option for Patients with Non-Small-Cell Lung Cancer

et al. 2016

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Lung cancer has a high mortality rate and is often diagnosed at the metastatic stage. Gefitinib is a targeted molecular therapeutic drug used to treat patients with non-small-cell lung cancer (NSCLC). Korean herbal medicines may also have therapeutic efficacy against lung cancer, reduce the side effects associated with chemotherapy, and improve patient quality of life (QOL). This case report describes the effects of a Korean herbal medicine regimen combined with gefitinib in a patient with NSCLC and bone metastasis. The Korean herbal medicine regimen included woohwanggeosa-dan, hwanggibujeong-dan and geonchilgyebok-jeong. The computed tomography (CT) findings showed that following combination treatment, the size of the tumor was markedly decreased without serious adverse events. Moreover, the Eastern Cooperative Oncology Group (ECOG) performance status was improved and cancer-related pain was decreased. These results suggest that a combination of Korean herbal medicines and gefitinib may be an effective therapeutic option for patients with advanced NSCLC and bone metastasis. Further studies are needed to examine the mechanism and the clinical efficacy of Korean herbal medicines against NSCLC.Lung cancer has a high mortality rate and is often diagnosed at the metastatic stage. Gefitinib is a targeted molecular therapeutic drug used to treat patients with non-small-cell lung cancer (NSCLC). Korean herbal medicines may also have therapeutic efficacy against lung cancer, reduce the side effects associated with chemotherapy, and improve patient quality of life (QOL). This case report describes the effects of a Korean herbal medicine regimen combined with gefitinib in a patient with NSCLC and bone metastasis. The Korean herbal medicine regimen included woohwanggeosa-dan, hwanggibujeong-dan and geonchilgyebok-jeong. The computed tomography (CT) findings showed that following combination treatment, the size of the tumor was markedly decreased without serious adverse events. Moreover, the Eastern Cooperative Oncology Group (ECOG) performance status was improved and cancer-related pain was decreased. These results suggest that a combination of Korean herbal medicines and gefitinib may be an effective therapeutic option for patients with advanced NSCLC and bone metastasis. Further studies are needed to examine the mechanism and the clinical efficacy of Korean herbal medicines against NSCLC.

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Section: Discussionmentioning

confidence: 99%

Combination Therapy of Gefitinib and Korean Herbal Medicines Could be a Beneficial Option for Patients with Non-Small-Cell Lung Cancer

et al. 2016

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Systematic Review of Case Reports about Korean Medicine for Lung Cancer

et al. 2018

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This systematic review aimed to put the case reports of lung cancer on Korean medicine (KM) together and adopt the results in clinical practice. Methods: Researches were searched using the PubMed, EMBASE, OASIS, KoreanTK, KISTI, RISS, KISS, and NDSL. The search term were 'lung cancer' and KM. There was no restriction in year. Results: 1. Among the 48 studies, 68 patients were reported in total. The types of lung cancer were non-small-cell lung cancer (n=41) and small-cell lung cancer (n=6). 2. The number of patients who received KM therapy alone was 40. On the other hand, 25 patients were treated with KM and chemotherapy simultaneously. All case reports used herbal medicine except 2 studies. Other types of treatment were acupuncture, moxibustion, pharmacopuncture, cupping, meditation, etc. 3. Several efficacy evaluation variables were used such as tumor size, changes of symptoms, duration of survival, the quality of life, and so on. The safety was evaluated by checking adverse effects using blood test. 4. Regarding the tumor response, partial response was reported in 12 cases, stable disease was in 22 cases, 50% of the total cases, which is a high level of tumor response. Furthermore, all 11 cases with the evaluation on the length of survival showed prolonged survival than the expectancy of corresponding stage, with the stable quality of life. Conclusion: We have found that the applicability of KM for treatment of lung cancer through this review. Evidence based medicine can be realized by checking cases and applying them in clinical practice.

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A Case Report of Partial Remission of End-stage Pancreatic Cancer Patient with Liver Metastasis Treated with Chemotherapy and Integrated Medicine Therapy

Ko¹,

Jang²,

Jang³

et al. 2020

J Int Korean Med

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Me t h o d s :O n ep a n c r e a t i cc a n c e rw i t hl i v e rme t a s t a s i sp a t i e n tw a st r e a t e du s i n gI MTi nc o n j u n c t i o nw i t hGe mc i t a b i n e / A b r a x a n e s i n c eS e p t e mb e r2 0 1 9 .T h ec y c l ew a sr e p e a t e de v e r yf o u rwe e k sf o rat o t a lo f1 1t i me s .Att h es a met i me ,t h ep a t i e n twa s t r e a t e dwi t hI MT.Tu mo rs i z ewa sme a s u r e db ys c a n n i n gwi t hCo mp u t e dTo mo g r a p h y( CT) .Ad v e r s ee v e n t swe r ee v a l u a t e d u s i n gt h eNa t i o n a lCa n c e rI n s t i t u t eC o mmo nTe r mi n o l o g yCr i t e r i af o rA d v e r s eEv e n t s( NCI -CTC AE) ,v e r s i o n5 . 0 .

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A case report of a clinically diagnosed advanced lung cancer patient after treatment with Gunchilgyebok-Jung

Cited by 3 publications

References 0 publications

Combination Therapy of Gefitinib and Korean Herbal Medicines Could be a Beneficial Option for Patients with Non-Small-Cell Lung Cancer

Combination Therapy of Gefitinib and Korean Herbal Medicines Could be a Beneficial Option for Patients with Non-Small-Cell Lung Cancer

Systematic Review of Case Reports about Korean Medicine for Lung Cancer

A Case Report of Partial Remission of End-stage Pancreatic Cancer Patient with Liver Metastasis Treated with Chemotherapy and Integrated Medicine Therapy

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