ipomas are benign soft tissue neoplasms comprised of mature adipocytes encapsulated by a layer of connective fibrous tissue. There are four histologic types of lipomas; 1 I. Angiolipomas are potentially painful masses that arise after puberty. They often have vascular network. II. Pleomorphic lipomas occur predominantly in men aged between 50 to 70 years old. They contain multinucleated giant cells along with normal adipocytes. III. Spindle cell Lipomas contain slender spindle cells.