A case report of metastatic malignant granular cell tumor of femoral soft tissue origin.

Isaka, Akira; Watanabe, Takanori; Oomori, Kastuji; Hakozaki, Hando; Ootsuki, Fumiko; Hiruta, Michiko; Yoshida, Kyoko; Mashiko, M

doi:10.5795/jjscc.28.970

Cited by 3 publications

(3 citation statements)

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“…As there are reports of malignant changes after a long-term follow up, caution is advised. 14 In conclusion, we experienced a case of a granular cell tumor occurring in the suprasternal space and report the importance of including it in the differential diagnosis of subcutaneous soft tissue tumors.…”

Section: Discussionmentioning

confidence: 92%

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Granular cell tumor of the suprasternal space

Ihara

Ito

Nakajima

et al. 2010

The Journal of Dermatology

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A case of granular cell tumor (GCT) was reported. We encountered a 33-year-old woman with a painless, elastic, hard mass in the soft tissue of the suprasternal space. The tumor was excised with several millimeters margin of normal tissue above the deep cervical fascia and the wound was closed primarily. Histological examination on hematoxylin-eosin stain showed a tumor growth in the mid- to deep dermis and eosinophilic small granules that were consistent with granular cell tumors. Immunohistochemical studies showed positive staining for S-100 protein. We experienced a case of a granular cell tumor occurring in the suprasternal space and report the importance of including it in the differential diagnosis of subcutaneous soft tissue tumors.

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Section: Discussionmentioning

confidence: 92%

“…Malignant tumors such as dermatofibrosarcoma protuberans, squamous cell carcinoma and breast cancer are also important differential diagnosis. As there are reports of malignant changes after a long‐term follow up, caution is advised 14 …”

Section: Discussionmentioning

confidence: 99%

Granular cell tumor of the suprasternal space

Ihara

Ito

Nakajima

et al. 2010

The Journal of Dermatology

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“…Recently, doses of 60 Gy or more have been reported to produce optimum control of malignant nerve sheath tumors (45) following gross tumor resection with negative margins. Chemotherapy has been tried on a few patients (16,44,46,47) unsuccessfully.…”

Section: Discussionmentioning

confidence: 99%

Malignant granular cell tumor of the vulva in a 17-year-old: Case report and literature review

Ramos¹,

Kapp²,

Longacre³

et al. 2000

Int J Gynecol Cancer

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Granular cell tumors are uncommon soft tissue tumors. Although the majority of these tumors are benign, a rare malignant variant exists which is aggressive, with local recurrence rates up to 70% and 3-year survival rates of less than 50%. We present a case of malignant granular cell tumor of the vulva in a 17-year-old, the sixth such case to be reported at this site. She was treated with a left hemivulvectomy and ipsilateral groin node dissection followed by postoperative radiation therapy. She remains free of disease at 16 months. Patients with malignant granular cell tumor or granular cell tumor of malignant potential are best managed with wide local excision and regional lymph node dissection.

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