A Case Report of Rotational Thromboelastometry-Assisted Decision Analysis for Two Pregnant Patients With Platelet Storage Pool Disorder

Abstract

Platelet storage pool disorders (PSPDs) constitute a diverse group of hematologic abnormalities, which share the common feature of a deficiency in the ability of platelets to aggregate. Parturients with PSPD can present management challenges to their care team when they present for childbirth, especially with regard to neuraxial anesthesia. We report a series of 2 deliveries from unrelated patients affected by PSPD. In particular, we highlight the utility of rotational thromboelastometry (ROTEM) and the need for a multidisciplinary approach to the care of patients with this hematologic abnormality.

Point-of-Care Testing in Patients with Hereditary Disorders of Primary Hemostasis: A Narrative Review

“…However, the vast majority of these studies consists of case reports involving patients undergoing surgical procedures 136 137 138 139 140 141 142 143 144 145 or during peripartum care. 146 147 148 149 150 151 152…”

“…However, the vast majority of these studies consists of case reports involving patients undergoing surgical procedures [136][137][138][139][140][141][142][143][144][145] or during peripartum care. [146][147][148][149][150][151][152] In GT, viscoelastic assays unequivocally have shown decreased clot strength (MA/maximal clot firmness). 126,[153][154][155][156] Using TEG Platelet Mapping, it was even possible to identify a GT patient with a mild bleeding phenotype from four other patients with more severe bleeding tendencies, 83 which suggests that this technique might be an attractive method to monitor GT patients.…”