A Case Report of Solitary, Intraosseous, Adult-Onset Myofibroma of the Mandible

Abstract

Myofibroma is a benign proliferation of myofibroblasts in the connective tissue. Solitary intraosseous myofibromas are a rare finding especially in an adult. Myofibroma is a benign lesion and its treatment is similar to any other benign lesion.This article reports a rare case of a 32 year old lady presenting with a complaint of a painful swelling in the lower third molar region, on examination the tender swelling had expansion of the buccal cortex. The diagnostic work up included OPG radiograph, CT Scan, and a deep incisional biopsy of the mass under L.A. The final diagnosis of myofibroma was made only after the histopathological diagnosis and Immunohistochemistry (IHC). The patient was treated with wide local excision of the lesion in the mandible under GA.

Intraosseous Myofibroma of the Mandible: A Case Report

“…Brasileiro et al (2010) mentions the development of this neoplasm at early ages. Allon et al (2007) observed that from 19 cases of mandible intraosseous myofibroma in the literature and four more included at the time, the mean age was 7.2 years; this paper agrees with other authors that have reported solitary mandible myofibroma in adult ages in the third and fourth decades of life (Oliver et al, 2003;Ramadorai et al, 2010;Sundaravel et al;Brierley et al, 2012).…”

Solitary Intra-Osseous Myofibroma of the Jaw: A Case Report and Review of Literature

“…It shows predilection for the lower jaw, as is seen in this particular case. Posterior regions of the lower jaw are affected more often than the anterior region [ 2 , 4 , 7 ]. Thus far in the literature, only two cases of IM involving the upper jaw have been documented [ 2 ].…”

“…It has two distinct clinical presentations: solitary and multicentric [ 1 , 2 , 3 ]. Solitary myofibroma in the oral and maxillofacial region is uncommon (accounts for 2% of all cases) and usually affects the oral and peri-oral soft tissues [ 4 ]. Intra-osseous myofibroma (IM) of the jaw bones is sporadic and shows a predilection for the lower jaw [ 3 , 5 ].…”

Imaging Features of Intraosseous Myofibroma of the Jaws: A Case Report and Literature Review

“…Papers not in English as the primary language were excluded. The inclusion strategies yielded 23 papers that contained reports of cases to include in our tabulation of imaging findings [1,4,7,[9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28]. The total number of patients with usable, individualized imaging data included in the selected papers was 30, and by including our reported case, the total was n=31.…”