A case report on trichoblastoma in Labrador dog

Sawale, G.K.; Gavhane, Dnyaneshwar S.; Mhase, A.K.; Rohi, R.R.; Moregaonkar, S. D.

doi:10.5958/0973-970x.2015.00091.7

Cited by 2 publications

(3 citation statements)

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“…(Hendrick, 2020). Skin sections show dense variably sized proliferating cells with oval to round nuclei (Sawale et al, 2014). Our gross and microscopic findings in our study were similar to those of Hendrick (2020);and Sawale et al (2014).…”

Section: Discussionsupporting

confidence: 83%

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Immunohistochemical expression of vimentin, E-cadherin, and CD45 in natural cases of canine cutaneous round tumors

Oda,

Tawfik,

Othman

et al. 2024

Braz. J. Biol.

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Round cell tumors are common cutaneous lesions in dogs, with increased occurrence percentages among different skin tumors. This study aimed to investigate the frequency as well as gross and pathological characteristics of round cell tumors in natural cases of tumorous dogs in relation to breed, sex, and age. Moreover, it aimed to evaluate the immunohistochemical expression of a panel of immunohistochemical stains, including vimentin, E-cadherin, and cluster of differentiation (CD45) as an adjunct technique for the differential diagnosis of cutaneous round cell neoplasm. Data were collected from 64 dogs of both sexes (36 females and 28 males), various breeds, and different ages (8 months to 7 years). The histopathological nature of neoplastic growth was reported, and neoplasm prevalence was classified using age, sex, breed, and site on the body. We observed 48 cases of transmissible venereal tumors, 12 cutaneous histiocytomas, and 4 histiocytic sarcoma. Immunohistochemical characterization revealed an intense positive immunoreactivity for vimentin in transmissible venereal tumor cells and moderate positive immunoreactivity for E-cadherin and CD45 in cutaneous histiocytoma and histiocytic sarcoma cells. In conclusion, the canine transmissible venereal tumor was the most frequent form of round cell tumor; thus, a definitive cutaneous neoplasm diagnosis should be based on histopathological morphology and immunohistochemical findings.

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Section: Discussionsupporting

confidence: 83%

“…Skin sections show dense variably sized proliferating cells with oval to round nuclei (Sawale et al, 2014). Our gross and microscopic findings in our study were similar to those of Hendrick (2020);and Sawale et al (2014). Also, Canine histiocytic sarcomas are locally aggressive, quickly developing tumors that only affect one place.…”

Section: Discussionsupporting

confidence: 78%

Immunohistochemical expression of vimentin, E-cadherin, and CD45 in natural cases of canine cutaneous round tumors

Oda,

Tawfik,

Othman

et al. 2024

Braz. J. Biol.

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“…More than one tumor subtype may be present and coexist in the same neoplasm as reported by Sawale et al (2015) and Mineshige et al (2014). The most common subtypes of trichoblastoma in dogs are granular and ribbon types whereas the trabecular and fusiform patterns are the ones most frequently diagnosed in cats (Goldschmidt & Goldschmidt, 2016;Mauldin & Kennedy, 2015).…”

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confidence: 80%

Trabecular trichoblastoma in a domestic cat (Felis catus domesticus, Linnaeus 1758)

Freitas¹,

Jorge²,

Silva³

et al. 2019

Braz. J. Vet. Res. Anim. Sci.

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Trichoblastoma is characterized as a benign cutaneous neoplasm that originates in the trichoblastic epithelium of the hair bulb. The present report describes the case of a 4-year-old cross breed neutered male cat that had a history of a slow, freely movable, ulcerated, slow growing, solitary cutaneous nodule located on the left scapular region. Histopathological evaluation showed neoplastic cells arranged in cohesive nests or palisades with eosinophilic and scant cytoplasm. Based on the microscopic findings, a diagnosis of trabecular trichoblastoma was made. The treatment of choice consisted of total surgical excision of the mass with safe surgical margins. Tumor recurrence was not observed.

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A case report on trichoblastoma in Labrador dog

Cited by 2 publications

References 0 publications

Immunohistochemical expression of vimentin, E-cadherin, and CD45 in natural cases of canine cutaneous round tumors

Immunohistochemical expression of vimentin, E-cadherin, and CD45 in natural cases of canine cutaneous round tumors

Trabecular trichoblastoma in a domestic cat (Felis catus domesticus, Linnaeus 1758)

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