A Case Report: Rare Case of Primary Transitional Cell Carcinoma of the Fallopian Tube

Abstract

Carcinomas other than adenocarcinomas are extremely rare in the fallopian tube. A 42-year-old woman with watery, intermittent vaginal discharge was found to have a left adnexal tumor. This case was diagnosed as primary carcinoma of the fallopian tube, FIGO Stage Ia. She underwent a total abdominal hysterectomy, a bilateral salpingo-oophorectomy, a pelvic and periaortic lymphoadenectomy, and an omentectomy, followed by cisplatin-based chemotherapy. Four years after the initial diagnosis of the disease, she remains in a disease-free state. Histologically, the tumor revealed a primary transitional cell carcinoma of the left fallopian tube. The findings on an immunohistochemical test for an epithelial membrane antigen, the CA125 antigen, were positive, whereas findings on a test for CEA were negative. We report a case of a malignant neoplasm of the fallopian tube with histological features of transitional cell carcinoma that arose from the tubal epithelium.

Primary Transitional Cell Carcinoma of Fallopian Tube: A Rare Entity with Review of Literature

“…direct extension, dissemination to ovaries, peritoneum and trans-peritoneal seeding. [6] TCCFTs can also present with an abnormal pap smear. Adenocarcinoma was reported in 0% -23% of cases in cervical cytology Treatment is based on the lines of EOC.…”

Presurgical diagnostic difficulties in an asymptomatic patient with primary transitional cell carcinoma of the oviduct: case report

“…Federman and Toker in 1973 described for the first time TCC of the oviduct [ 10 ]. A few cases of primary TCC of fallopian tubes have been reported in the literature [ 4 , 11 , 12 ]. Keepanasseril et al .…”

“…A history of profuse intermittent vaginal discharge was the only symptom reported by Takeuchi et al ., while lower abdominal pain and backache were the sole symptoms reported by Kim et al . [ 4 , 11 ]. The tumor marker CA125 is not necessarily elevated [ 4 ].…”