A Case Report Surgical Treatment for Parathyroid Adenoma: A Case Report

Abstract

BACKGROUND:Parathyroid adenoma is a rare disease. This article aimed to present the classic symptoms, diagnosis, and management of parathyroid adenoma.CASE REPORT:We report the case of a 24-year-old Asian woman with a several-month-long history of prolonged fatigue, bone, and joint pain. The patient was admitted to our hospital with multiple fractures without significant trauma. Physical examination revealed no palpable masses in the neck. The bone survey showed multiple fractures and osteoporosis of the humerus, clavicle, femur, and lumbar vertebrae. The laboratory workup showed a significantly elevated parathyroid hormone (PTH) level of 1,276 pg/ml (reference range: 10-55 pg/ml) and hypercalcemia, at 11.3 mg/dl (reference range: 8.5-10.5 mg/dl). MRI revealed enlargement of the left inferior parathyroid gland. The patient was diagnosed with a parathyroid gland tumour. Surgical resection was performed, and histopathology revealed parathyroid adenoma. The clinical manifestations and PTH and calcium levels gradually decreased to normal after the surgery. At the two-year follow-up, there was no recurrence of the disease. The patient has resumed her daily life as a farmer.CONCLUSIONS:Parathyroid adenoma has an excellent prognosis with surgical treatment.

Brown Tumor Secondary to Hyperparathyroidism: A Case Report

“…Non-invasive methods consist of imaging studies like: ultrasonography, CT, MRI, or scintigraphy using technetium (Tc-99m) sestamibi [14]. Scintigraphy has a high sensitivity reaching around 80% in localizing a single adenoma, however this sensitivity drops to 25% when there are multiple adenomas [15]. Surgical management of parathyroid adenoma is by surgical exploration of the neck with subsequent removal of the adenoma, biopsy of another parathyroid gland is indicated if another adenoma or multiple gland hyperplasia is suspected [15].…”

Asymptomatic Hypercalcemia Due to Bilateral Parathyroid Adenoma: A Case Report

“…Clinically, the manifestations of this disease are associated with signs and symptoms of hypercalcemia. 10,11 Asymptomatic hypercalcemia is most often found incidentally. If symptoms are present, a parathyroid adenoma may manifest as an enlarged gland in the neck that can be painful.…”

“…Physical examination may reveal a lump in the neck, neurological disorders, and multiple fractures. 11 Investigations showed increased calcium levels and parathyroid hormone, which led to the suspicion of primary hyperparathyroidism.…”

A case report: acute necrotizing pancreatitis secondary to hypercalcemia in case of parathyroid adenoma

“…It is vital to take into account the superior exploration of the mediastinum if a parathyroid tumor was not discovered. 6 The surgical procedure most frequently used to treat primary hyperparathyroidism is minimally invasive parathyroidectomy. The best application of intraoperative PTH monitoring is as a supplement to preoperative imaging, enabling more targeted surgeries.…”