A Case Series of Contact Lens-Associated Fusarium Keratitis in Hong Kong

Abstract

This cluster of Fusarium keratitis seems to be related to the use of the ReNu MoistureLoc contact lens solution. The cure rate with medical therapy was 66%. However, corneal scarring limited visual recovery. This episode highlights the need for clinical vigilance when dealing with corneal infiltrates in contact lens users.

Pythium insidiosum Keratitis in Contact Lens Wear: A Case Report

“…[34][35][36][37][38][39][40] However, there is an escalating trend of soft contact lensrelated ulcerative keratitis resulting from fungi. [41][42][43][44][45][46][47][48] Fusarium, Aspergillus, Candida, and Curvularia are the most common causes. [47][48][49] Although Pythium keratitis has occasionally been described in the literature, 10,11,[19][20][21]26 Pythium has never been isolated in patients with contact lens-related microbial keratitis.…”

Treatment options in emerging mold infections

“…However, in the case of Fusarium keratitis, topical treatment with natamycin (eye drops) is standard and sometimes is combined with an oral antifungal, such as itraconazole. Medical response rates are above 60% [26]. Disseminated infections in immunocompromised hosts deserve special attention because of their poor prognosis.…”

Antimicrobial Efficacy Tests of Multipurpose Contact Lens Care Solutions Simulating Poor Contact Lens Hygiene Behaviors

“…Recently, an outbreak of Fusarium keratitis, a rare fungal infection, has been linked to contact lens (CL) wear in Singapore, 1,2 Hong Kong, 3 and the United States. 4 This fungal epidemic among CL wearers strongly implicated one specific multipurpose solution (MPS), ReNu with Moisture Loc.…”