A Case Series of COVID-19 Respiratory Infection in Hospitalized Children: Clinical and Computed Tomography Challenges

Abstract

: Our objective was to evaluate clinical and computed tomographic features in hospitalized children with COVID-19 infection who were admitted to the pediatric center of excellence, children’s medical center. In this case-series, we report twelve patients with clinical symptoms of acute respiratory infections at the beginning or after admission who have PCR-proved (throat swab samples) COVID-19 infection and underwent computed tomography imaging. Six patients had an underlying disease and atypical findings with no clinical suspicion at the beginning. Tachypnea (75%) represented the most common physical finding. Computed tomography was abnormal in 83.3% of patients. Subpleural consolidation, peribronchial thickening, round consolidation, and Halo sign was depicted. The empirical regimen in our hospital included hydroxychloroquine and oseltamivir. Some of the patients managed easily, but others had prolonged hospital stay, especially patients with significant underlying conditions.

Computed tomography findings in 3,557 COVID-19 infected children: a systematic review

“…This review included 81 articles published in English that in total included 3,557 pediatric patients. Of these, 2 were from the USA (46,86), was from Kore (58), 1 was worldwide ( 70 (46,47,75,81,82,90,104,108), 2 letters (77,79), 1 brief report (36), 2 case-control study (49,101), 2 cohort studies (66,70), 1 observational (84) and 5 observational cohort study (80,93,99,100,113) and the remained articles were descriptive studies. A total of 84 variables were extracted for this review.…”

“…), 5 were from Turkey(66,72,92,99,107), 7 were from Iran(43,69,71,95,97,104,106), 2 were from Italy(87,112), 2 were from Brazil (96,114), 1 was from Egypt (85), 1 was from the Latin America (108), 1 was from France (105), 2 was from the UAE (91,93), 1 was from Portugal(113) and the remained 55 studies were from China. All of them were published in 2020-21.Among the 81 studies, 14 investigated children and adults(36…”