A case series of myocardial infarction in SARS‐CoV‐2‐infected patients: Same complication, different outcomes

Alizadehasl, Azin; Eslami, Samira; Vakili, Kimia; Khorasani, Shirin Habibi; Haghazali, Mehrdad; Khalilipur, Ehsan

doi:10.1002/ccr3.5304

Cited by 2 publications

(1 citation statement)

References 37 publications

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“…COVID-19 infection has been reported to be associated with both arterial and venous thromboembolism (VTE) such as pulmonary embolism (PE), cerebrovascular accident (CVA), acute myocardial infarction (AMI), renal artery thrombosis, and mesenteric ischemia [ 7 ]. The exact pathophysiology for this increased thrombotic risk is unclear, although immune system hyperactivity with cytokine storm, local and systemic inflammatory reactions, and diffuse microthrombi are the possible mechanisms that contribute to this higher thromboembolic risk in COVID-19 patients [ 7 , 8 ]. Myocardial injury has been reported in up to 12% of hospitalized patients with COVID-19 and 20% patients requiring admission to ICU [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Prolonged Use of Tirofiban Infusion Without Percutaneous Coronary Intervention To Achieve Optimal Results in a COVID-19 Positive Patient With Inferior ST Segment Elevated Myocardial Infarction (STEMI) Secondary to Thromboembolism: A Case Report

Khan¹,

Patel²

2022

Cureus

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Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), responsible for COVID-19, is mainly a respiratory illness, but it can affect other organs also such as heart, kidneys, and liver. Myocardial injury from COVID-19 has been reported in hospitalized patients ranging from pericarditis and myocarditis to acute coronary syndrome (ACS). COVID-19 is highly hypercoagulable state and is associated with both central and peripheral thromboembolism. COVID 19 patients with ACS may not present with classical features of chest pain and electrocardiogram (ECG) is the most important initial investigation in these patients to assess for any ST or T waves changes. COVID-19 patients with cardiac involvement are the most vulnerable group of patients and have increased morbidity and mortality risk. COVID-19 infections can affect the cardiovascular system in patients with or without history of coronary artery disease (CAD), but the risk of type 1 or 2 myocardial infarction (MI), myocardial injury, ST segment elevation, myocarditis, heart failure, cardiogenic shock, and life threatening arrhythmias are more common in the former group. We present a case of 55-year-old patient who presented to our cardiac center with ST elevated myocardial infarction and high blood sugar level. Patient was recently diagnosed with type 2 diabetes mellitus (T2DM) but was not commenced on medications. Echocardiogram showed mildly impaired left ventricular systolic function (LVSF) with inferior wall hypokinesia, and ECG showed inferior leads ST elevation. Coronary angiogram showed severe mid-vessel lesion and occluded posterior left ventricular branch (PLV). Multiple attempts at aspirating the thrombus resulted in thrombolysis in MI grade 2 (TIMI 2) flow in the vessel and patient was commenced on a tirofiban infusion for 72 hours.

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Section: Discussionmentioning

confidence: 99%

Prolonged Use of Tirofiban Infusion Without Percutaneous Coronary Intervention To Achieve Optimal Results in a COVID-19 Positive Patient With Inferior ST Segment Elevated Myocardial Infarction (STEMI) Secondary to Thromboembolism: A Case Report

Khan¹,

Patel²

2022

Cureus

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Azithromycin/hydroxychloroquine

2022

Reactions Weekly

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A case series of myocardial infarction in SARS‐CoV‐2‐infected patients: Same complication, different outcomes

Abstract: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 2 publications

References 37 publications

Prolonged Use of Tirofiban Infusion Without Percutaneous Coronary Intervention To Achieve Optimal Results in a COVID-19 Positive Patient With Inferior ST Segment Elevated Myocardial Infarction (STEMI) Secondary to Thromboembolism: A Case Report

Prolonged Use of Tirofiban Infusion Without Percutaneous Coronary Intervention To Achieve Optimal Results in a COVID-19 Positive Patient With Inferior ST Segment Elevated Myocardial Infarction (STEMI) Secondary to Thromboembolism: A Case Report

Azithromycin/hydroxychloroquine

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