Objectives: Aims were (1) to determine the proportion of patients with lumbar impairments who could be classified at intake by McKenzie syndromes (McK) and pain pattern classification (PPCs) using Mechanical Diagnosis and Therapy (MDT) assessment methods, manipulation, and stabilization clinical prediction rules (CPRs) and (2) McK -derangement 67%, dysfunction 5%, posture 0%, other 28%; PPC -CEN 43%, Non CEN 39%, NC 18%; manipulation CPR -positive 13%; Stab CPR -positive 7%. For patients positive for manipulation CPR (n579), prevalence rates for derangement were 89% and CEN 68%. For patients positive for stabilization CPR (n541), prevalence rates for derangement were 83% and CEN 80%. Discussion: The majority of patients classified based on initial clinical presentation by manipulation and stabilization CPRs were also classified as derangements whose symptoms centralized. Manipulation and stabilization CPRs may not represent a mutually exclusive treatment subgroup but may include patients who can be initially treated using a different classification method.