A catalyst-free, green and efficient protocol for the synthesis of methyleneisoxazole-5(4H)-ones supported by ultrasonic irradiation

Bankuru, Jyothi; Battula, Venkateswara Rao; Tirumala Santhoshkumar, S.; Gopal, Sidama; Meena, Ram Pratap; Ahmed, N. Zaheer

doi:10.1016/j.jciso.2023.100097

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Preprint2

Article1

Relationship

Self Cite0

Independent3

Authors

Journals

Cited by 3 publications

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Green waves in medicinal chemistry: ultrasound driven multicomponent reactions for sustainable synthesis of biologically active molecules

Kardani,

Vaghani,

Patel

2024

Phosphorus, Sulfur, and Silicon and the Related Elements

View full text Add to dashboard Cite

Green waves in medicinal chemistry: ultrasound driven multicomponent reactions for sustainable synthesis of biologically active molecules

Kardani,

Vaghani,

Patel

2024

Phosphorus, Sulfur, and Silicon and the Related Elements

View full text Add to dashboard Cite

RETRACTED: Ultrasound-Assisted Synthesis of Novel 4-Oxo-Chromen-Dihydropyridine Derivatives by a One-Pot Fusion and Multicomponent Reaction under Environmentally Friendly Conditions

Potnuru,

Mamidi,

Lagudu

et al. 2024

Preprint

View full text Add to dashboard Cite

A highly efficient, environmentally friendly, and sustainable protocol has been developed for the synthesis of novel substituted 4-oxo-chromen-dihydropyridine derivatives which includes the exploitation of a one-pot fusion and a multicomponent reaction consisting of different aromatic and heteroaryl amines, malononitrile, dimethyl acetylenedicarboxylate, and chromene-3-carbaldehyde in EtOH medium under ultrasound irradiation at ambient temperature. From an economical and environmentally beneficial perspective, this approach is extremely intriguing due to the use of green solvents and catalyst-free circumstances. By using NMR and HRMS spectroscopic investigation, we were able to confirm the structures of the synthesized dihydropyridine analogs. For the first time, this methodology primarily provides an array of advantages, including ease of handling, a cleaner reaction, convenience of operation, a straightforward work-up system, good yields (97–96%), a rapid reaction time (≤ 10 min), and reduced environmental effects. Outstanding yields of 4-oxo-chromen-dihydropyridine analogues, easy setup mechanism, free column chromatography, eco-friendly solvent, quick reaction at ambient temperature, and superior functional group tolerance are the benefits of this protocol.

show abstract

RETRACTED: Ultrasound-Assisted Synthesis of Novel 4-Oxo-Chromen-Dihydropyridine Derivatives by a One-Pot Fusion and Multicomponent Reaction under Environmentally Friendly Conditions

Potnuru,

Mamidi,

Lagudu

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

A catalyst-free, green and efficient protocol for the synthesis of methyleneisoxazole-5(4H)-ones supported by ultrasonic irradiation

Cited by 3 publications

References 31 publications

Green waves in medicinal chemistry: ultrasound driven multicomponent reactions for sustainable synthesis of biologically active molecules

Green waves in medicinal chemistry: ultrasound driven multicomponent reactions for sustainable synthesis of biologically active molecules

RETRACTED: Ultrasound-Assisted Synthesis of Novel 4-Oxo-Chromen-Dihydropyridine Derivatives by a One-Pot Fusion and Multicomponent Reaction under Environmentally Friendly Conditions

RETRACTED: Ultrasound-Assisted Synthesis of Novel 4-Oxo-Chromen-Dihydropyridine Derivatives by a One-Pot Fusion and Multicomponent Reaction under Environmentally Friendly Conditions

Contact Info

Product

Resources

About