A causal link between circulating leukocytes and three major urologic cancers: a mendelian randomization investigation
Yi Zhi-gang,
Wang Han-dong
Abstract:PurposeThis study aimed to explore the influence of serum leukocytes on urologic cancers (UC) using observation-based investigations. In the present study, Mendelian randomization (MR) was employed to assess the link between leukocyte count (LC) and the risk of UC development.MethodsFive LC and three major UC patient prognoses were obtained for MR analysis from genome-wide association studies (GWAS). Furthermore, in order to evaluate reverse causality, bidirectional studies were conducted. Finally, a sensitivi… Show more
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