A causality dilemma: ARFID, malnutrition, psychosis, and hypomagnesemia

Wassenaar, Elizabeth; O’Melia, Anne; Mehler, Philip S.

doi:10.1002/eat.22939

Cited by 7 publications

(5 citation statements)

References 14 publications

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“…Whilst similar levels of dietary restriction were observed in the cohorts studied, patients with ARFID were found to display clinically-distinct presentations compared to those with other EDs, including a history of abdominal pain, a longer length of illness and a distinct absence of any cognitions relating to weight or body image (Nakai et al, 2017;Becker et al, 2018;Izquierdo et al, 2018;Lieberman et al, 2019). Several case studies (n = 6) also reported that ARFID can develop in the context of various secondary medical or psychiatric illnesses, including food avoidance associated with drug use (Lazare, 2017), dietary restriction due to gastrointestinal discomfort following surgery (Tsai et al, 2017) and two cases of ARFID occurring alongside psychosis (Wassenaar et al, 2018;Westfall et al, 2018).…”

Section: Clinical Characteristicsmentioning

confidence: 99%

Avoidant/restrictive food intake disorder: A systematic scoping review of the current literature

Bourne

Bryant‐Waugh

Cook

et al. 2020

Psychiatry Research

114

105

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Avoidant/restrictive food intake disorder (ARFID) was recently introduced to psychiatric nosology to describe a group of patients who have avoidant or restrictive eating behaviours that are not motivated by a body image disturbance or a desire to be thinner. This scoping review aimed to systematically assess the extent and nature of the ARFID literature, to identify gaps in current understanding, and to make recommendations for further study. Following an extensive database search, 291 unique references were identified. When matched against pre-determined eligibility criteria, 78 full-text publications from 14 countries were found to report primary, empirical data relating to ARFID. This literature was synthesised and categorised into five subject areas according to the central area of focus: diagnosis and assessment, clinical characteristics, treatment interventions, clinical outcomes, and prevalence. The current evidence base supports ARFID as a distinct clinical entity, but there is a limited understanding in all areas. Several possible avenues for further study are indicated, with an emphasis placed on first parsing this disorder's heterogeneous presentation. A better understanding of the varied mechanisms which drive food avoidance and/or restriction will inform the development of targeted treatment interventions, refine screening tools and impact clinical outcomes.

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Section: Clinical Characteristicsmentioning

confidence: 99%

Avoidant/restrictive food intake disorder: A systematic scoping review of the current literature

Bourne

Bryant‐Waugh

Cook

et al. 2020

Psychiatry Research

114

105

View full text Add to dashboard Cite

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“…To our knowledge, the only prior mention of this comorbidity was a case report of a patient with ARFID and Gitelman syndrome. 36 Anxiety and depression…”

Section: Discussionmentioning

confidence: 99%

Neurodevelopmental and psychiatric conditions in 600 Swedish Children with the ARFID phenotype

Nyholmer,

Wronski,

Hog

et al. 2024

Preprint

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Objective: Avoidant restrictive food intake disorder (ARFID) is a feeding and eating disorder characterized by extremely restricted dietary variety and/or quantity resulting in serious consequences for physical health and psychosocial functioning. ARFID often co-occurs with neurodevelopmental conditions (NDCs) and psychiatric conditions, but previous data are mostly limited to small clinical samples examining a narrow range of conditions. Here, we examined NDCs and psychiatric conditions in a large, population-based group of children with ARFID. Method: In a sample of 30,795 children born 1992-2008 in Sweden, ARFID was assessed using parent reports and clinical diagnoses from national health registers. Parents further reported symptoms of NDCs and psychiatric conditions at child age 9 or 12 years. We conducted regressions for symptom scores and screening diagnoses (identified using validated cut offs) on ARFID and examined interactions with sex. Results: Children with ARFID had significantly increased odds of all 17 screening diagnoses with odds ratios ranging from 3.3 for visual hallucinations to 13.7 for autism (all p<.0001). The most common NDCs were oppositional defiant disorder (19.4%), ADHD (16.9%), tic disorders (14.8%), and autism (12.1%). Among psychiatric conditions, separation anxiety disorder (29.0%) and sleep problems (20.0%) had the highest prevalence. We did not find any sex-specific differences in co-occurring conditions. Conclusion: This study highlights the co-occurrence of a broad range of NDCs and psychiatric conditions with ARFID in a large, non-clinical cohort. Our findings underscore that children with ARFID face significant burden from multiple co-existing conditions which should be considered during assessment and treatment.

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“…The remaining 267 articles were examined according to the eligibility criteria mentioned above for possible selection; 220 articles were eliminated. Finally, 47 articles were chosen for analysis, nevertheless, six articles were excluded because three of them provided a diagnosis other than ARFID (Lazare, et al, 2017;Toufexis, et al 2015;Wassenaar et al, 2018) and the remaining three articles were used to exemplify characteristics or research ideas and/or did not apply clinical intervention (Kreipe & Palomaki, 2012;Lucarelli, et al, 2017;Menzel, et al, 2018). Figure 1 presents the flowchart of the screening process.…”

Section: Study Selectionmentioning

confidence: 99%

Avoidant/Restrictive Food Intake Disorder (ARFID): Review of Case Studies

Medina‐Tepal¹,

Arévalo

Vacuán³

et al. 2023

Rev. Mex. Trast. Alim.

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Karla Medina-Tepal) GRANT SPONSOR: PAPIIT-IN306518 Conflicto de intereses: Los autores declaran no tener conflicto de intereses. ResumenEl Trastorno de evitación/restricción de la ingesta de alimentos (TERIA) tiene una presentación clínica compleja. Desde su reconocimiento en el DSM-5 se han realizado investigaciones que aportan datos de esta condición, sin embargo, su tratamiento se ha reportado mayormente en estudios de casos. Por tanto, el objetivo del presente estudio fue analizar las características e intervenciones clínicas de estudios y series de casos del TERIA, a partir de una revisión de la literatura con base a los lineamientos PRISMA y CARE. En total se examinaron 41 artículos, la mayoría de los casos reportados fueron en hombres (53.85%) con edades entre 10 a 13 (29.23%), aunque, 15.38% de los casos tenían un rango de edad de 20 a 56 años. En cuanto a sus síntomas, el más frecuente fue el bajo peso (66.15%), sin embargo, 3.08% de estos pacientes presentaba sobrepeso ligado al consumo de carbohidratos. Las comorbilidades psiquiátricas más frecuentes fueron los trastornos de ansiedad (38.46%). Por último,

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A causality dilemma: ARFID, malnutrition, psychosis, and hypomagnesemia

Cited by 7 publications

References 14 publications

Avoidant/restrictive food intake disorder: A systematic scoping review of the current literature

Avoidant/restrictive food intake disorder: A systematic scoping review of the current literature

Neurodevelopmental and psychiatric conditions in 600 Swedish Children with the ARFID phenotype

Avoidant/Restrictive Food Intake Disorder (ARFID): Review of Case Studies

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