“…AFM can be applied in materials science (morphology, electrical, magnetic and mechanical properties) (Vlassov et al, 2018; Wang et al, 2021), physics (many physical properties of materials are detected, including those in nanophysics, mesophysics and microscopic physics) (Chen & Xu, 2020; Dufrêne et al, 2021; Zhu, Tan, & Hong, 2021), chemistry (in situ detection for chemical reactions in a controlled environment, surface chemical reactions and changes at the atomic level) (Abarghani et al, 2020; Labidi et al, 2017; McDonald et al, 2020; Silbernagl et al, 2021), biology (movement and morphology of DNA, RNA, protein and cells, in situ high‐resolution liquid imaging of interactions between membranes and viruses, protein folding molecular forces, biological macromolecules, and cell surface antigens (Amarouch et al, 2018; Pi & Cai, 2019), and surface treatments for cutting DNA, microtubules, and other small fibres) (Bitler et al, 2018; Chen & Xu, 2020; Chiorcea‐Paquim et al, 2018; Hubert et al, 2019; Main et al, 2021; Schön, 2018), microelectronics (large‐scale integrated circuit detection, local electrical properties of integrated circuit (IC), storage and reading of ultrahigh density optical/magnetic information) (Yuan et al, 2017, 2020; Zhang et al, 2018), and medicine (a powerful tool for mesoscopic and nanoscopic research on biological cells, combining an inverted biological microscope, fluorescence microscope, fluorescence energy resonance transfer microscope and confocal microscope, which are widely used in medicine, pharmacology, immunology, therapy, nanoscopic research, etc.) (Chen & Xu, 2020; Silbernagl et al, 2021; Yang, 2016; Zhou et al, 2021).…”