“…Definitely, there exist other sophisticated methods, e.g., Markov random field based segmentation [6,44,18,14], multilevel, resp., scale-space approaches [20], anisotropic filtering [3] segmentation based on genetic algorithms [47,13,22], neural networks [48,1], hybrid segmentation techniques [32], statistical procedures [19,49,2] and adaptive weight smoothing [33]. A qualitative and quantitative comparison of conventional segmentation operators was tested for small samples (Fig.…”