A cementless hip system with a new surface for osseous integration

Lass, Richard; Kolb, Alexander; Skrbensky, Gobert von; Reinisch, Georg; Kubista, Bernd; Giurea, Alexander; Windhager, Reinhard; Kotz, R.

doi:10.1007/s00264-013-2135-7

Cited by 14 publications

(8 citation statements)

References 28 publications

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“…This illustrates that initial metal-bone contact, while sometimes invisible on the radiograph, exists in both cup designs. This is corroborated by the good long-term and short-term clinical successes of the 2D and 3D cup designs respectively [10] , [11] , [12] , [13] , [16] , [17] , [24] , [25] , [31] .…”

Section: Discussionmentioning

confidence: 78%

“…Porous coated uncemented acetabular components are commonly used in total hip arthroplasty with good long-term survival [9] , [10] , [11] , [12] , [13] , [16] , [17] , [25] . Conversely, retrieval studies have shown that bone fixation occurs on a relatively small percentage of the available porous surface and fibrous growth is commonly present on many acetabular implants with porous surfaces [9] , [28] .…”

Section: Discussionmentioning

confidence: 99%

“…In clinical practice, 2D and 3D modified acetabular components have demonstrated good outcomes and survivorship [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] The Trident Primary Acetabular Component (Stryker, Mahwah, NJ) has a 2D surface coating of arc-deposited commercially pure titanium. First released in the late 1990s, the Trident has demonstrated long-term clinical success in multiple studies [10] , [11] , [12] , [13] , [14] , [15] . A more recently introduced device with a 3D surface is the Tritanium Primary Acetabular Component (Stryker).…”

Section: Introductionmentioning

confidence: 99%

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Radiolucencies surrounding acetabular components with three-dimensional coatings: artifact or real?

et al. 2017

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BackgroundSeveral 2-dimensional and 3-dimensional surfaces are available for cementless acetabular fixation. Plain radiographs are used to assess osseointegration; however, the radiographs are limited by their inability to capture the bone fixation process occurring over the 3-dimensional cup surface. In this cadaveric study, we compared the bone apposition between 2-dimensional and 3-dimensional cups.MethodsBoth types of cups were implanted in 6 cadavers and pelvic radiographs obtained. Each cup was resected from the pelvis with adequate bone around it, and subsequently embedded in a polymer. Six sections of each cup were obtained to examine the metal and bone interface. Photographs and contact radiograph images were obtained for each section, and these were graded to arrive at percent metal-bone contact values for the cups.ResultsOn average, <30% of the cups' areas displayed radiolucencies on the pelvic radiographs for both cup types. For the section images and radiographs, there was about 80% aggregate contact between the cups and surrounding bone in both cup types. In the 3-dimensional cups group, some inconsistencies were found between the section photographs and the corresponding radiograph images. The radiolucencies observed on the section radiograph could not always be correlated with metal to bone gap on the section photograph.ConclusionsGood metal-bone contact (75% + contact area) was observed on both cup types. The inconsistencies found in the 3-dimensional cup group may be because of the interaction of radiographs with the unique porous cup surface resulting in artifactual radiolucencies.

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Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Radiolucencies surrounding acetabular components with three-dimensional coatings: artifact or real?

et al. 2017

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“…Total hip replacement is considered by many to be the most important operation developed in the 20th century in terms of relieving the amount of human suffering . Increased efforts were made to improve osseointegration of these implants by modification of their surface properties . Today, hydroxyapatite coatings of titanium stems are successfully used in hip arthroplasty like the Corail ® hip system (Depuy Co., Warsaw, IN) .…”

Section: Introductionmentioning

confidence: 99%

“…[6][7][8] Increased efforts were made to improve osseointegration of these implants by modification of their surface properties. [9][10][11] Today, hydroxyapatite coatings of titanium stems are successfully used in hip arthroplasty like the Corail V R hip system (Depuy Co., Warsaw, IN). 12 In recent research, these surfaces were further modified to release rhBMP-2 and found to significantly alter bone volume close to the interface.…”

Section: Introductionmentioning

confidence: 99%

Osteogenic differentiation and proliferation of bone marrow‐derived mesenchymal stromal cells on PDLLA + BMP‐2‐coated titanium alloy surfaces

Haversath

Hülsen

Böge

et al. 2015

J Biomedical Materials Res

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RhBMP-2 is clinically applied to enhance bone healing and used in combination with titanium fixation implants. The purpose of this in vitro study was to compare the osteogenic differentiation and proliferation of hMSC on native polished versus sandblasted titanium surfaces (TS) and to test their behavior on pure poly-D,L-lactide (PDLLA) coated as well as PDLLA + rhBMP-2 coated TS. Furthermore, the release kinetics of PDLLA + rhBMP-2-coated TS was investigated. Human bone marrow cells were obtained from three different donors (A: male, 16 yrs; B: male, 27 yrs, C: male, 49 yrs) followed by density gradient centrifugation and flow cytometry with defined antigens. The cells were seeded on native polished and sandblasted TS, PDLLA-coated TS and PDLLA + rhBMP-2-coated TS. Osteogenic differentiation (ALP specific activity via ALP and BCA assay) and proliferation (LDH cytotoxicity assay) was examined on day 7 and 14 and release kinetics of rhBMP-2 was investigated on day 3, 7, 10, and 14. We found significant higher ALP specific activity and LDH activity on native polished compared to native sandblasted surfaces. PDLLA led to decreased ALP specific and LDH activity on both surface finishes. Additional rhBMP-2 slightly diminished this effect. RhBMP-2-release from coated TS decreased nearly exponentially with highest concentrations at the beginning of the cultivation period. The results of this in vitro study suggest that native TS stimulate hMSC significantly stronger toward osteogenic differentiation and proliferation than rhBMP-2 + PDLLA-layered TS in the first 14 days of cultivation. The PDLLA-layer seems to inhibit local hMSC differentiation and proliferation.

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