A challenge for blood management: A patient presenting <scp>anti‐Vel</scp> antibody undergoing orthotopic liver transplantation

de Freitas Dutra, Valéria; Yokoyama, Ana Paula Hitomi; de Rezende, Marcelo Bruno; Felga, Guilherme Eduardo Gonçalves; Kutner, José Mauro; Bonet‐Bub, Carolina

doi:10.1111/tme.12996

Cited by 1 publication

(1 citation statement)

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“…A recent report in the hematology literature for a patient undergoing LT with a different rare anti-Vel antibody reinforces these considerations. 13 With more stable liver function in this report (MELD 16), there was time for preoperative optimization with iron therapy and erythropoietin which allowed for autologous donation and collection. Similar to our case, intraoperative cell salvage was used, hemostatic management was facilitated with a visco-elastic coagulation monitor ROTEM (Werfen Inc) and 2 frozen stored RBC units that had been prepared, were not required.…”

Section: Discussionmentioning

confidence: 91%

Blood Management in a Liver Transplant Recipient with Kidd (Jka) and Rhesus (D) Antibodies: A Case Report

Butler,

Hundley,

Lin

et al. 2024

A&A Practice

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A 67-year-old man presented for urgent liver transplantation (LT). Screening revealed the rare combination of antiRhesus (D) and antiKidd Jk(a) antibodies, requiring antigen-negative red blood cells (RBC) for both phenotypes. This combination has not been reported during LT. Compatible RBCs were initially limited, requiring continued communication between the blood bank/blood supplier to obtain more, including frozen, units. Additional strategies included the use of cell salvage and intentional management of coagulopathy to limit bleeding and RBC requirement. This case highlights blood management during LT when D and Jk(a) antibodies may limit RBC supply and emphasizes the need for effective communication with the blood bank.

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Section: Discussionmentioning

confidence: 91%