A Childhood Illness … in an Adult

Navaravong, Leenhapong; Cui, Jiang; Stoenescu, Mathias

doi:10.1016/j.amjmed.2010.05.003

Cited by 2 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, a case-report in 2010 by Navaravong et al reported on a 43-year-old man with asymptomatic bradycardia found to exhibit a late presentation of complete CHB (CCHB) with an unknown etiology. 2 In this case, the patient was asymptomatic with a normal heart structure and function. His ECG and exercise test findings were compatible with atrioventricular nodal block.…”

Section: Long-term Follow Up and Adult Issuesmentioning

confidence: 78%

“…49 Additionally, traditional RV pacing in children with CHB has been shown to precipitate immediate cardiomyopathy and acute heart failure in a select group of patients—namely in patients of mothers with connective tissue disease. 2,23,50,51 …”

Section: Long-term Follow Up and Adult Issuesmentioning

confidence: 99%

“…1 Since we are heading into an era where more patients with structural or functional (cardiomyopathic or arrhythmic) congenital heart defects will be over the age of 21 years, 2,3 cases will increasingly present to adult cardiologists.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Cardiac Manifestations of Neonatal Lupus

Capone

Buyon

Friedman

et al. 2012

Cardiology in Review

View full text Add to dashboard Cite

Within the last decade the prevalence of adult patients living with congenital heart disease equals that seen in children. This expanding population poses a challenge to clinical cardiologists who will be caring for patients with the clinical manifestations of this condition. Neonatal lupus is a model of passively acquired auto-immunity and is responsible for the majority of clinical cases of congenital heart block. This review will focus on the presentation, pathophysiology, and the long-term follow up of congenital heart block associated with neonatal lupus, as well as discuss important diagnostic tests, familial implications, and pacemaker issues associated with the care of an adult with congenital heart block.

show abstract

Section: Long-term Follow Up and Adult Issuesmentioning

confidence: 78%

Section: Long-term Follow Up and Adult Issuesmentioning

confidence: 99%

See 1 more Smart Citation

Cardiac Manifestations of Neonatal Lupus

Capone

Buyon

Friedman

et al. 2012

Cardiology in Review

View full text Add to dashboard Cite

show abstract

Autoimmune congenital heart block: complex and unusual situations

Brito-Zerón

Izmirly

Ramos‐Casals

et al. 2016

Lupus

View full text Add to dashboard Cite

Autoimmune congenital heart block (ACHB) is an immune-mediated cardiac disease included among the manifestations collectively referred to as neonatal lupus. The placental transference of maternal Ro/La autoantibodies may damage the conduction tissues during fetal development leading to blocking of signal conduction at the atrioventricular (AV) node in an otherwise structurally normal heart. Irreversible complete AV block is the main cardiac manifestation of ACHB, but some babies may develop endocardial fibroelastosis, valvular insufficiency, and/or frank cardiomyopathies with significantly reduced cardiac function requiring transplant. The severity of ACHB is illustrated by a global mortality rate of 20% and pacemaker rates of at least 64%, often within the first year of life. This review analyses the main complex and/or unusual clinical situations associated with ACHB, including unusual maternal immunological profiles, infrequent maternal autoimmune diseases, cardiac damage unrelated to AV block, fetal invasive management, late complications after birth, risk of congenital heart block (CHB) in ovodonation and in vitro fertilization techniques, the role of maternal features other than autoimmunity, the influence of the birth order or the risk of CHB in twins and triplets.

show abstract

A Childhood Illness … in an Adult

Cited by 2 publications

References 11 publications

Cardiac Manifestations of Neonatal Lupus

Cardiac Manifestations of Neonatal Lupus

Autoimmune congenital heart block: complex and unusual situations

Contact Info

Product

Resources

About