2023
DOI: 10.4103/eus-d-22-00058
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A Chinese prospective multicenter cohort study evaluating EUS-guided drainage of pancreatic fluid collections using the Hot AXIOS system

Abstract: Background and Objectives: The Hot AXIOS system, which features a cautery-enhanced lumen-apposing metal stent, facilitates EUS-guided transmural drainage of pancreatic fluid collection (PFC). We aimed to evaluate the safety and efficacy of stents in a multicenter Chinese cohort. Patients and Methods: Thirty patients from nine centers with a single pancreatic pseudocyst (PP) or walled-off necrosis (WON) who underwent EUS-guided transgastric or transduode… Show more

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Cited by 6 publications
(3 citation statements)
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“…In a multicenter study involving 313 patients, Siddiqui et al compared LAMS to DPPS and FCSEMS in the management of WOPN and showed that LAMS were more likely to have early adverse events on multivariable analysis [ 9 ]. In a recent prospective multicenter study evaluating cautery-enhanced (“hot”) LAMS for PFCs, Li et al reported a stent occlusion rate of 10% and a stent migration rate of about 7% [ 28 ]. Our analysis shows that the odds of overall adverse events were 2.2 times lower when DPPS was used concurrently with LAMS, and this was statistically significant.…”
Section: Discussionmentioning
confidence: 99%
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“…In a multicenter study involving 313 patients, Siddiqui et al compared LAMS to DPPS and FCSEMS in the management of WOPN and showed that LAMS were more likely to have early adverse events on multivariable analysis [ 9 ]. In a recent prospective multicenter study evaluating cautery-enhanced (“hot”) LAMS for PFCs, Li et al reported a stent occlusion rate of 10% and a stent migration rate of about 7% [ 28 ]. Our analysis shows that the odds of overall adverse events were 2.2 times lower when DPPS was used concurrently with LAMS, and this was statistically significant.…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, earlier studies included in this meta-analysis reported using both cautery-enhanced and non-cautery-enhanced LAMS [ 19 - 21 ]. Studies have demonstrated a reduction in the risk of LAMS-related bleeding with the introduction of cautery-enhanced systems [ 28 - 30 ]. This suggests that the mechanism by which DPPS can improve outcomes and the affected outcomes could vary, depending on the type of PFCs and the type of LAMS used.…”
Section: Discussionmentioning
confidence: 99%
“…In contrast, TMD can be accomplished across the duodenal or gastric wall under EUS, requiring pseudocysts to be close to the gastrointestinal wall (<1 cm). Metal stents, particularly the innovative Hot AXIOS system, are preferred for EUS-TMD in treating PPCs due to their efficacy and safety, as demonstrated by Li et al [ 4 ]. If a pseudocyst does not heal after a single drainage procedure, a combination of TPD and TMD may be considered, although the benefits of such a combined approach remain limited and controversial, as outlined in Table 2 .…”
Section: Discussionmentioning
confidence: 99%