A conformal geometry determines a distinguished, potentially singular, variant of the usual Yamabe problem, where the conformal factor can change sign. When a smooth solution does change sign, its zero locus is a smoothly embedded separating hypersurface that, in dimension three, is necessarily a Willmore energy minimiser or, in higher dimensions, satisfies a conformally invariant analog of the Willmore equation. In any case the zero locus is critical for a conformal functional that generalises the total Q-curvature by including extrinsic data. These observations lead to some interesting global problems that include natural singular variants of a classical problem solved by Obata.