A Clinic-Epidemiological Study of Head and Neck Tuberculosis—A Single-Center Experience

Pajor, Anna; Józefowicz-Korczyńska, Magdalena; Korzeniewska-Koseła, Maria; Kwiatkowska, Sylwia

doi:10.5603/arm.2016.0042

Cited by 7 publications

(4 citation statements)

References 19 publications

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“…In fact, more than 62.9% of laryngeal TB patients were reported before the year 2007. In the study by Pajor, which included patients from 1978 to 2013, the larynx was also found to be the most common site of HNTB 18 . Therefore, studies only including patients in the most recent ten years may reach a different conclusion.…”

Section: Discussionmentioning

confidence: 99%

“…Because the early manifestation of HNTB is often similar to neoplasms or inflammation and because the systemic symptoms of tuberculosis may not be obvious, clinical consideration of HNTB usually occurs only after an ineffective anti-inflammatory treatment, biopsy, or even surgical resection 2 , 12 – 16 . Despite the large number of existing reports, the patient risk of medical injury and occupational exposure caused by a delayed diagnosis of HNTB does not seem to have decreased over the past decade 17 , 18 .…”

Section: Introductionmentioning

confidence: 99%

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Clinical study of tuberculosis in the head and neck region—11 years’ experience and a review of the literature

Pang

Duan

Liu

et al. 2018

Emerging Microbes & Infections

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Tuberculosis (TB) is an infectious disease and major health concern. Head and neck tuberculosis (HNTB) is relatively rare, but can arise in many regions, including the lymph nodes, larynx, oral cavity and pharynx. We retrospectively reviewed the clinical records of 60 patients diagnosed with HNTB in our department between March 2005 and January 2016. A review and summary of previous HNTB articles published in PubMed since 1885 was also performed. The subjects consisted of 17 males and 43 females, and the average age of patients was 45 ± 14.67 years. The major clinical presentation was a lump or swelling, followed by an oral ulcer and skin fistula. The most common site of tuberculosis was in the cervical lymph node. Three patients also suffered from a malignant tumor in the head and neck region. A total of 980 papers involving 5881 patients were included in our literature review. The included subjects ranged in age from 15 months to 100 years with a male-to-female ratio of 1.5:1. The larynx (38.92%), cervical lymph nodes (38.28%) and oral cavity (9.92%) were the three most common development sites. 465 patients were positive according to a HIV test, and 40 patients had comorbidities with different types of tumors. Head and neck tuberculosis should always be considered during a differential diagnosis for lesions in the head and neck region. Early diagnosis and treatment can greatly enhance the therapeutic effect and patients’ quality of life.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Clinical study of tuberculosis in the head and neck region—11 years’ experience and a review of the literature

Pang

Duan

Liu

et al. 2018

Emerging Microbes & Infections

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“…Because manifestations of TB in the head and neck are clinically similar to inflammation or neoplasms, and because of its rarity in low prevalence regions, clinical consideration of TB as a differential diagnosis often occurs quite lately 14,15 and has not decreased in the past few decades 16 . In this regard, an origin in a region with high prevalence of TB in the population or family members with a known or suspected history of TB can lead to an earlier diagnostic suspicion 4 .…”

Section: Introductionmentioning

confidence: 99%

Tuberculosis in the Head and Neck: Changing Trends and Age‐Related Patterns

et al. 2021

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To evaluate changing trends in patient collectives, age-related patterns of manifestation, and diagnostic pathways of patients with extrapulmonary head and neck tuberculosis (TB), and to provide strategies to fasten diagnosis in these patients.Study design: Case control study. Methods: A 10-year retrospective analysis of 35 patients diagnosed with extrapulmonary TB in the head and neck at a tertiary university institution from 2009 to 2019, with special focus on the influence of the patient's age on consideration of TB and clinical patterns.Results: The vast majority of patients younger than 40 years had their origin in countries with high TB burden (P = .0003), and TB was considered very early as a differential diagnosis (P = .0068), while most patients older than 40 years were domestic citizens initially suspected for a malignancy, who more often had an underlying immunosuppressive condition (0.0472). Most frequent manifestations in both groups were the lymph nodes, larynx, and oropharynx. Surprisingly, no differences in the rates of open TB or history of TB infection in the family anamnesis were found. Conclusion:The two groups of patients found most often are younger patients migrating from regions with high TB burden and elderly domestic patients suffering from immunosuppressive conditions, with the latter often being misdiagnosed as malignancies. TB remains an important but difficult differential diagnosis, due to the initially unspecific symptoms and the great variety in the presentation of manifestations in the head and neck.

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“…There are a number of recent case series of extrapulmonary TB from low-risk countries, although these are not directly applicable to the UK population. [11][12][13][14][15] In 2006, Menon et al published a series of 128 patients with head and neck TB in Bradford, which had a relatively high incidence of TB compared with the UK average. 16 This series confirmed lymph node predominant disease but also demonstrated the diverse ways in which TB can present in the head and neck.…”

Section: Introductionmentioning

confidence: 99%

Cervical tuberculous lymphadenitis: diagnosis and demographics, a five-year case series in the UK

Moualed

Robinson

Qureishi

et al. 2018

annals

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Introduction Cervical tuberculous lymphadenitis is a low-volume condition in the UK with a potential for delayed diagnosis. This study describes typical demographic and clinical features of patients diagnosed with cervical tuberculous lymphadenitis in a UK population. The utility of cytological, histological and microbiological investigations is reviewed with comparison between fine-needle aspiration and open biopsy. This information can facilitate recognition of new cases and guide initial management. Methods Patients diagnosed with cervical tuberculous lymphadenitis between January 2009 and December 2013 at two district general hospitals were identified from local infectious disease databases. Retrospective case-note review was undertaken to collect demographic and diagnostic data and associated complications. Results Full data were available for 51 patients aged 19–70 years (mean 32.4 years) with mean follow-up of 370 days; 49/51 patients were immigrants to the UK with a wide geographic spread in the countries of origin and time since arrival; 42/51 had no significant comorbidities, although two patients had coexistent HIV infection. The clinical presentation was most frequently without constitutional symptoms (39/51) and often with no history of tuberculosis contact. Posterior triangle neck nodes were most commonly involved (26/51). Conclusion The ‘typical’ patient with cervical tuberculous lymphadenitis in our region is a young healthy individual who came to the UK from a high-risk country several years earlier. Diagnosis by fine-needle aspiration is as effective as open biopsy if fluid/pus is aspirated. Open biopsy is potentially associated with complications but does not appear to increase chronic wound discharge rates in our series.

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A Clinic-Epidemiological Study of Head and Neck Tuberculosis—A Single-Center Experience

Cited by 7 publications

References 19 publications

Clinical study of tuberculosis in the head and neck region—11 years’ experience and a review of the literature

Clinical study of tuberculosis in the head and neck region—11 years’ experience and a review of the literature

Tuberculosis in the Head and Neck: Changing Trends and Age‐Related Patterns

Cervical tuberculous lymphadenitis: diagnosis and demographics, a five-year case series in the UK

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