A clinical case of acute myeloid leukemia mimicking a tumor of the Ewing sarcoma family

Abstract

Relevance: M6 variant of acute myeloid leukemia is extremely rare
 in pediatric practice. The diverse clinical manifestations of erythroblastic leukemia complicate the timely diagnosis of this group of diseases.
 Purpose: to describe a clinical case of congenital erythroblastic
 leukemia with multiple lesions of soft tissues and the skeletal system
 with complications in the form of the convulsive syndrome, presented
 as an Ewing’s sarcoma tumor, diagnosed at the Research Center of
 Pediatrics and Pediatric Surgery (Almaty, the Republic of Kazakhstan).
 Results: The presented clinical case demonstrated challenges in
 diagnosing and treating young patients with multiple life-threatening
 tumor lesions. The need to develop molecular genetic studies and expand diagnostic capabilities is an integral part of treating oncohematological diseases.
 Conclusion: The presented clinical case is of great interest due
 to its rareness. This case confirms the need to conduct all diagnostic manipulations to assess the process prevalence and to choose and conduct molecular genetic studies on all stages of examination and treatment.