A clinical case of hemorrhagic syndrome with simultaneous use of amiodarone and warfarin in an elderly patient

Abstract

The article considers a clinical case of an adverse drug reaction with simultaneous use of amiodarone and warfarin, manifested by hemorrhagic syndrome. It also provides an overview of data available from domestic and foreign sources regarding the drug interaction of warfarin and amiodarone, as well as the features of pharmacotherapy in elderly patients, including the features of pharmacodynamics in this group of patients. The main result of the presented literature review is the conclusion that doctors in their practice should take into account the possibility of drug interaction and pay attention to this section in the instruction leaflets of medicinal products, especially in the treatment of an elderly patient.