A clinical review of 38 cases of cervical tuberculous lymphadenitis in Japan – The role of neck dissection

Omura, Sayaka; Nakaya, Muneo; Mori, Ayumi; Oka, Mineko; Ito, Akiko; Kida, Wataru; Inayoshi, Yasuhiro; Inoue, A.; Fuchigami, Teruhiko; Takamori, Mikio

doi:10.1016/j.anl.2016.01.002

Cited by 13 publications

(6 citation statements)

References 17 publications

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“…At present, CTL is mainly treated using systematic application of anti-tuberculosis chemotherapy, the Infectious Disease Society of America (IDSA) guideline recommends surgical excision only in unusual circumstances, disease caused by drugresistant organism, or paradoxical upgrading reactions ( 6 , 24 , 25 ). CTL with different stages of procession require different treatment methods, type I and type IV are the early and healing phases for the lesion, respectively, and systematic anti-tuberculosis chemotherapy can be used, while there are diverse clinical interventions for types II and III CTL, such as tuberculous abscess that has not ruptured can be subjected to puncture and aspiration.…”

Section: Discussionmentioning

confidence: 99%

Value of Contrast-Enhanced Ultrasound in the Ultrasound Classification of Cervical Tuberculous Lymphadenitis

Zhang

et al. 2022

Front. Med.

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PurposeThe purpose of this study was to investigate the clinical value of contrast-enhanced ultrasound (CEUS) in the ultrasound (US) classification of cervical tuberculous lymphadenitis (CTL).Materials and MethodsThis retrospective study included 70 patients diagnosed with CTL. All patients underwent both conventional US and CEUS. Both methods were compared to determine their agreement with pathological CTL results.ResultsThe results of conventional US classification were as follows: 18 patients (25.7%) were type I, 25 patients (35.7%) type II, 21 patients (30.0%) type III, and 6 patients (8.6%) type IV, respectively. The results of CEUS classification were as follows: 9 patients (12.9%) were type I, 33 patients (47.1%) type II, 22 patients (31.4%) type III, and 6 patients (8.6%) type IV. Conventional US classification and pathological results showed moderate agreement in terms of US classification results for CTL (Kappa = 0.693); the accuracy of conventional US classification was 78.6% (55/70), and the accuracy of types II and III were 71.0% (22/31) and 82.6% (19/23), respectively. CEUS classification and pathological results showed strong agreement (Kappa = 0.871); the accuracy of CEUS classification was 91.4% (64/70), and the accuracy of types II and III were 93.6% (29/31) and 87.0% (20/23), respectively.ConclusionIn combined with conventional US, CEUS could provide more information on blood flow enhancement patterns and identify the area of lymph node necrosis in CTL. This could contribute to a more accurate US classification of CTL.

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Section: Discussionmentioning

confidence: 99%

Value of Contrast-Enhanced Ultrasound in the Ultrasound Classification of Cervical Tuberculous Lymphadenitis

Zhang

et al. 2022

Front. Med.

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“…Currently, TB is spreading at a high pace both locally and globally. At present, multiple drug therapy is the preferred treatment for tuberculous lymphadenitis [3,4].…”

Section: Discussionmentioning

confidence: 99%

“…However, surgery, without the use of rifampicin and pyrazinamide, was one of the preferred treatments for peripheral lymph node TB until the early 1990s [3,6,7]. In 1997, the World Health Organization recommended a sixmonth regimen for the treatment of patients with category III TB, which includes lymph node TB; subsequently, reports concerning the use of surgery for the treatment of cervical tuberculous lymphadenitis after 1993 have been absent [3]. In our case, a large sinus formed and failed to heal after surgery.…”

Section: Discussionmentioning

confidence: 99%

“…Tuberculosis (TB) is the second most common infectious disease associated with mortality worldwide [1,2]. The World Health Organization estimates that two billion people in the world have latent TB, and up to 3 million people die of TB every year [3]. The most common extrapulmonary manifestation of this disease still occurs in peripheral lymph nodes [2,4].…”

Section: Introductionmentioning

confidence: 99%

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Anterolateral Thigh Myocutaneous Flap for Reconstruction of a Large Anterior Neck Sinus Caused by Tuberculous Lymphadenitis: a Case Report

Jiao

Liu

Gan

et al. 2020

SN Compr. Clin. Med.

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Tuberculosis remains a major global health problem and persistent lymphadenitis or incorrect treatment may result in sinus formation. We present a case of a large anterior neck sinus caused by tuberculous lymphadenitis. We designed an anterolateral thigh myocutaneous flap with 6 × 5 cm of skin and 10 × 7 cm of muscle for the reconstruction of the large sinus. The descending branch of the lateral circumflex femoral artery and 2 venae comitantes were anastomosed with superior thyroid arteries and two anterior neck veins. The patient experienced complete survival of the flap and did not complain of any discomfort. The donor site healed well, and weakness of the lower limb was absent. In conclusion, an anterolateral thigh myocutaneous flap is a good choice for the reconstruction of a neck sinus caused by tuberculous lymphadenitis.

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“…Ultrasound contrast agent was obtained from Sonovi (Brazil, Italy); its main component was sulfur hexafluoride. Distribution of the color Doppler flow in the lymph nodes was observed, and the results of the flow distribution were divided into four types: no blood flow, marginal blood flow, mixed blood flow, or central blood flow [ 9 , 10 ].…”

Section: Methodsmentioning

confidence: 99%

The value of multimodal ultrasonography in differential diagnosis of tuberculous and non-tuberculous superficial lymphadenitis

Chu

Zhang

et al. 2021

BMC Surg

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Background To investigate the value of multimodal ultrasonography in differentiating tuberculosis from other lymphadenopathy. Methods Sixty consecutive patients with superficial lymphadenopathy treated at our hospital from January 2017 to December 2018 were categorized into four types based on the color Doppler ultrasound, five types based on contrast-enhanced ultrasound, and five types based on elastography. Sensitivity and specificity were calculated of all the three imaging, including color Doppler examination, contrast-enhanced ultrasound and one individual multimodal method, for detecting lymph nodes. Results A total of 60 patients were included in the final analysis. Of those, Mycobacterium tuberculosis was positive in 38 patients and negative in 22 patients. Among the 38 patients who were positive for Mycobacterium tuberculosis, of which 23 had a history of pulmonary tuberculosis, accounting for 60.53% of the positive cases, and the remaining patients did not combine lesions of other organs. Among the 60 superficial lymph nodes, 63.3% presented with tuberculous lymphadenitis. The sensitivity, specificity, and accuracy of the color Doppler examination were 73.68%, 68.18%, and 71.67%, respectively. The sensitivity, specificity and accuracy of contrast-enhanced ultrasound were 89.47%, 63.64% and 80.00%, respectively. The sensitivity, specificity and accuracy of the elastography were 63.16%, 63.64% and 63.33%, respectively. The sensitivity, specificity and accuracy of one individual multimodal method were 42.11%, 95.45% and 61.67%, respectively. The sensitivity, specificity and accuracy of all modes combined were 100.00%, 27.27% and 73.33%, respectively. Conclusion Multimodal ultrasonography has high predictive value for the differential diagnosis of superficial tuberculous lymphadenitis.

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A clinical review of 38 cases of cervical tuberculous lymphadenitis in Japan – The role of neck dissection

Cited by 13 publications

References 17 publications

Value of Contrast-Enhanced Ultrasound in the Ultrasound Classification of Cervical Tuberculous Lymphadenitis

Value of Contrast-Enhanced Ultrasound in the Ultrasound Classification of Cervical Tuberculous Lymphadenitis

Anterolateral Thigh Myocutaneous Flap for Reconstruction of a Large Anterior Neck Sinus Caused by Tuberculous Lymphadenitis: a Case Report

The value of multimodal ultrasonography in differential diagnosis of tuberculous and non-tuberculous superficial lymphadenitis

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