A clinical sign of adenocystic tumour of the trachea

Adenoid cystic carcinoma of the tracheobronchial tree in five patients was treated surgically and the clinicopathologic manifestations and histogenesis were examined in detail. Symptoms such as cough, dyspnea, hemoptysis, and atelectasis on chest X-ray were present in four patients, and the other patient was asymptomatic. Histologically, growth patterns were classified as tubular, cribriform, and solid. The solid pattern was the most aggressive with extensive perineural invasion. Immunohistochemically, secretory component, lactoferrin, and epithelial membrane antigen were present in the cells lining the gland-like lumen of tissues with the tubular and cribriform patterns, but was rare in those with a solid pattern. Desmin and S-100 protein were detected in the nonlining cells of tissues with all three patterns. These findings suggest that this tumor originates from the myoepithelial cells of the bronchial gland and that the solid pattern was the most poorly differentiated form.

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Adenoid cystic carcinoma of the tracheobronchial tree: Clinicopathology and immunohistochemistry

Ishida

Nishino

Oka

et al. 1989

Journal of Surgical Oncology

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Tumores broncopulmonares benignos y tumores primitivos de la traquea

Muñoz

Trueba

Ugarte

1980

Archivos de Bronconeumología

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Reconstruction of Trachea and Bronchus

Ishihara

1978

J.Jpn.Bronchoesophagol.Soc.

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A clinical sign of adenocystic tumour of the trachea

Cited by 3 publications

References 4 publications

Adenoid cystic carcinoma of the tracheobronchial tree: Clinicopathology and immunohistochemistry

Adenoid cystic carcinoma of the tracheobronchial tree: Clinicopathology and immunohistochemistry

Tumores broncopulmonares benignos y tumores primitivos de la traquea

Reconstruction of Trachea and Bronchus

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