Background: Among women, abnormal uterine bleeding and infertility rates are rapidly increasing. The clinician generally prefers physical examination, methodical histopathology report to diagnose the pregnancy related disorders, systemic conditions and disease related to the genital tract. Diagnostic hysteroscopy is a precious contrivance to diagnose widespread disorders and diseases related to female genital tract and uterus, such as abnormal uterine bleeding since hysteroscopy assists to understand the mechanism for the regulation of normal cycle. Methods: The study had been carried out in the Department of Obstetrics and Gynecology, Krishna Medical Center, Lucknow from September 2012 to July 2017. Total of 400 patients were included in this randomized study. The study allocated histopathologic analysis, diagnostic hysteroscopy, intervention with or without anesthesia and postoperative diagnosis of patients. Results: Of all the cases, who underwent diagnostic hysteroscopy, about 44% of cases were normal and 56% of cases were found with various abnormalities. 22% of cases had endometrial hyperplasia, 11% of cases had an endometrial polyp, 10% of cases had submucous myoma and 9% of cases had atrophy. On observing the clinical presentation, 42% of cases had menorrhagia, 20% of cases had polymenorrhoea, 16% of cases had metorrhagia and 22% of cases had reported with postmenopausal bleeding. About 60% of diagnostic hysteroscopies were performed without anesthesia, however, an ascending trend was reported for general anesthesia. Primary infertility was reported in 44% of cases and 56% of cases were reported with secondary infertility. Conclusion: Our study concluded that the patients with pregnancy-related disorders and disease related to the genital tract and uterus should first undergo diagnostic hysteroscopy to provide a diagnosis with high accuracy and specificity.