A clinical study of submandibular schwannoma

Multiple Schwannomas Arising in the Midline Space Between the Bilateral Genioglossus Muscles and Left Submandibular Space

“…3 Magnetic resonance imaging shows low-signal intensity in the T1-weighted image and highsignal intensity in the T2-weighted image. 3,4 Although target sign (biphasic pattern of peripheral hyperintensity and homogeneous central hypointensity on T2-weighted images) and reverse target sign (biphasic pattern central high intensity and peripheral low intensity on gadolinium-enhanced T1-weighted images) are specific to schwannomas, 3 the present case had no both signs. Although imaging modalities may provide some evidence for the correct diagnosis, confirmation ultimately requires pathologic examination.…”

“…In radiologic diagnosis, magnetic resonance imaging is most sensitive and specific in the diagnosis of schwannoma in the head and neck region 3. Magnetic resonance imaging shows low-signal intensity in the T1-weighted image and high-signal intensity in the T2-weighted image 3,4. Although target sign (biphasic pattern of peripheral hyperintensity and homogeneous central hypointensity on T2-weighted images) and reverse target sign (biphasic pattern central high intensity and peripheral low intensity on gadolinium-enhanced T1-weighted images) are specific to schwannomas,3 the present case had no both signs.…”

Unmasking Hypoglossal Nerve Schwannomas Mimicking Submandibular Salivary Gland Tumors: Case Report of a Rare Presentation and Surgical Management

“…However, due to their very nature, neural damages after surgical resection of salivary gland schwannoma are common, seen in more than 50% of cases [13]. A clinical study by Keon Woo Park et al [21] analyzed 61 cases diagnosed with schwannomas at the final biopsy after surgery. Three schwannomas (4.9%) developed in the submandibular space.…”

“…The possibility of recurrence also exists [21]. Recurrence is infrequent, and malignant transformation is rare.…”

Extracranial Hypoglossal Schwannoma: Case Report and Literature Review

“…Schwannomas are solitary, benign, slow-growing, and wellencapsulated neurogenic neoplasms originating from the myelin-producing Schwann cells of the peripheral nerves (1)(2)(3)(4)(5)(6). They can involve the cranial nerves, such as V, VII, X, XI, and XII or sympathetic and peripheral nerves (7)(8)(9)(10)(11). Approximately 25-45% of extracranial schwannomas are located in the head and neck region (7-9, 12, 13).…”