A clinical study of the effect of calcium sodium phosphosilicate on dentin hypersensitivity

Abstract

Objective: Dentinal hypersensitivity is a commonly encountered problem with varied treatment options for its management. A large number of home use products have been tested and used for the management of dentinal hypersensitivity. This 8 week clinical trial investigates the temporal efficacy of commercially available calcium sodium phosphosilicate containing toothpaste in comparison to a potassium nitrate containing toothpaste. Methods: A total 20 subjects between the ages of 18 to 65 years were screened for a visual analogue score (VAS) for sensitivity of 5 or more by testing with a cold stimulus and randomly divided into test and positive control groups. Baseline sensitivity VAS scores to air evaporative stimulus were recorded for minimum two teeth. The subjects were prescribed respective dentifrices and revaluated for sensitivity scores at 2, 4 and 8 weeks. Results:The study demonstrated reduction in symptoms for all treatment groups from baseline to 2, 4 and 8 weeks. The calcium sodium phosphosilicate group showed a higher degree of effectiveness at reducing hypersensitivity to air evaporative stimulus at 2 weeks, than commercially available potassium nitrate. However, there was no significant difference in scores of subjects using the calcium sodium phosphosilicate toothpaste as compared to potassium nitrate at 4 weeks and 8 weeks. Conclusion: Calcium sodium phosphosilicate showed greater reduction in sensitivity compared to potassium nitrate at an earlier stage which is of high clinical value. However, based on the findings of the present study long term effects of calcium sodium phosphosilicate seem to be less promising than previously claimed. Key words:Dentinal desensitizing agents, dentinal hypersensitivity, toothpaste, pain measurement.

Human Dentinal Tubules alterations after desensitizing Dentifrices use: An ex vivo study

“…Although some studies shows some substances as gold stantards in occluded tubules, specially Sodium Potassium Phosphosilicate [1,13,15,23,24,26,31,32], in our research all dentifrices were able to occluded dentinal tubules without any statistical difference. It could be seen at SEM images and qualitative analyses.…”

Management of dentine hypersensitivity: efficacy of professionally and self‐administered agents

“…, Acharya et al. ), the remainder having a moderate risk of bias. When assessing the quality of the body of evidence for professionally applied CSPS agents one study had a moderate risk of bias (Neuhaus et al.…”

“…, Acharya et al. ), strontium chloride (1) (Du Min et al. ) and stannous fluoride gel (1) (Sharma et al.…”

“…This review included consideration of 28 papers, of which 12 fulfilled the relevant criteria. The majority of CSPS papers were regarding toothpaste (10) (Du Min et al 2008, Litkowski & Greenspan 2010, Narongdej et al 2010, Pradeep & Sharma 2010, Salian et al 2010, Pradeep et al 2012, Surve et al 2012, Rajesh et al 2012, Acharya et al 2013, and the other two prophylaxis pastes (Milleman et al 2012, Neuhaus et al 2013. All studies were parallel in design, with 10 studies having the recommended 2 stimuli (Du Min et al 2008, Litkowski & Greenspan 2010, Narongdej et al 2010, Pradeep & Sharma 2010, Salian et al 2010, Milleman et al 2012, Pradeep et al 2012, Rajesh et al 2012, Neuhaus et al 2013.…”

Does Gingival Recession Require Surgical Treatment?

“…This rate of reduction in symptoms may not be different from that found for topical interventions; however there are no studies to date directly making this comparison. 39 …”