A clinical study of the coronal plane deformity in Parkinson disease

Ye, Xiaoyun; Lou, Danning; Ding, Xueping; Xie, Chengrong; Gao, Jixiang; Lou, Yue; Cen, Zhidong; Xiao, Yao; Miao, Qianzhuang; Xie, Fei; Zheng, Xiaosheng; Wu, Jianxin; Li, Fangcai; Luo, Wei

doi:10.1007/s00586-017-5018-6

Cited by 23 publications

(23 citation statements)

References 35 publications

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“…Currently, the Cobb angle is an objective radiographic parameter to quantify the severity of scoliosis on coronal radiographs [4]. A Cobb angle > 10° is considered clinically significant for scoliosis diagnosis [5], whereas the variability of Cobb angle measurements has been reported to range from 3° to 10° in previous studies [6]. In addition, manual measurement is time-consuming, especially in scoliosis screening.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of a computer-aided method for measuring the Cobb angle on chest X-rays

Pan

Chen²,

Chen

et al. 2019

Eur Spine J

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Objectives To automatically measure the Cobb angle and diagnose scoliosis on chest X-rays, a computer-aided method was proposed and the reliability and accuracy were evaluated. Methods Two Mask R-CNN models as the core of a computer-aided method were used to separately detect and segment the spine and all vertebral bodies on chest X-rays, and the Cobb angle of the spinal curve was measured from the output of the Mask R-CNN models. To evaluate the reliability and accuracy of the computer-aided method, the Cobb angles on 248 chest X-rays from lung cancer screening were measured automatically using a computer-aided method, and two experienced radiologists used a manual method to separately measure Cobb angles on the aforementioned chest X-rays. Results For manual measurement of the Cobb angle on chest X-rays, the intraclass correlation coefficients (ICC) of intra-and inter-observer reliability analysis was 0.941 and 0.887, respectively, and the mean absolute differences were < 3.5°. The ICC between the computer-aided and manual methods for Cobb angle measurement was 0.854, and the mean absolute difference was 3.32°. These results indicated that the computer-aided method had good reliability for Cobb angle measurement on chest X-rays. Using the mean value of Cobb angles in manual measurements > 10° as a reference standard for scoliosis, the computer-aided method achieved a high level of sensitivity (89.59%) and a relatively low level of specificity (70.37%) for diagnosing scoliosis on chest X-rays. Conclusion The computer-aided method has potential for automatic Cobb angle measurement and scoliosis diagnosis on chest X-rays.

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Section: Introductionmentioning

confidence: 99%

Evaluation of a computer-aided method for measuring the Cobb angle on chest X-rays

Pan

Chen²,

Chen

et al. 2019

Eur Spine J

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“…In other studies, Parkinson's disease was associated with a higher incidence of scoliosis in women. There was also a positive relationship between the severity of PD symptoms and the extent of scoliosis [27,28]. In my other studies, research was conducted in the area of postural stability analysis among PD patients.…”

Section: Discussionmentioning

confidence: 99%

Body posture in patients with Parkinson’s disease

Wilczyński

Półrola

2017

Balt J Health Phys Act

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Open Access License:This is an open access article distributed under the terms of the Creative Commons Attribution-Non-commercial 4.0 International (http://creativecommons.org/licenses/by-nc/4.0/), which permits use, distribution, and reproduction in any medium, provided the original work is properly cited, the use is non-commercial and is otherwise in compliance with the license. abstract BackgroundThe purpose of the study was to analyze changes in the body posture and to assess the differences in posture between women and men with PD. Material/MethodsA group of 32 patients were examined, who were members of the Parkinson's Disease Association in Kielce. Body posture was examined by an optoelectronic method -Diers formetric III 4D -using raster stereography. ResultsEnlarged chest kyphosis (hyperkyphosis) was observed in 11 (34.37%) individuals. Enlarged lumbar lordosis (hyperlordosis) occurred in 10 (31.25%) patients. Deepened chest kyphosis and lumbar lordosis (hyperkyphosis-hyperlordosis) was noted in 3 (9.37%) individuals. Scoliosis occurred in 28 (87.5%) patients while 4 patients (12.5%) showed signs of scoliotic posture. ConclusionsSignificantly more postural defects were observed in individuals with PD compared to those who were healthy. This is especially true in the case of scoliotic posture. Highly significant differences in posture variables were observed between males and females, concerning body height and mass, angle of lumbar lordosis, trunk length (VP-DM) and trunk length (VP-SP). Patients with PD require systematic rehabilitation, which is as important as pharmacological treatment. Key wordsParkinson's disease, body posture, curvature of the spine Parkinson's disease (Lat. morbus Parkinsoni) is one of the most common diseases of the nervous system. In the course of the disease a wide spectrum of disorders is observed, especially motor, cognitive, and emotional ones. Also disorders in the autonomic nervous system are observed. The disease often begins between the ages of 58-62; however, cases of its earlier development are also noted. It is estimated that the disease occurs in approximately 0.15% of the general population [1,2,3]. The morbidity risk in males is slightly higher compared to females [4,5]. It is estimated that in Poland about 80,000 people are ill with this disease. Apart from motor disorders (e.g. resting tremor, slowness of movements, muscle rigidity, disorders of posture and motor coordination) [6,7], there occur non-motor symptoms, including emotional disorders, cognitive disorders, vegetative symptoms, disorders concerning sleep and sensory sensitivity [8]. The cause of the development of Parkinson's disease has not been recognized to-date, and its treatment is limited to the symptomatic treatment. The pathomechanism of death of dopaminergic neurons has not been discovered. There are several etiologic hypotheses of Parkinson's disease, among others, the theory of environmental factors and toxins [9,10], the theory of genetic factors [11,12], the theory of premature ageing of t...

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Section: Introductionmentioning

confidence: 99%

“…In severe cases, PD causes postural disorder, such as anterocollis, Pisa syndrome, and camptocormia [2][3][4][5]. Reports have shown that these postural abnormalities increase susceptibility to rigid spinal deformities [2,3] and that patients with PD develop adult spinal deformity (ASD) more frequently than the general population in the same age groups [6].Recent studies have shown that ASD negatively affects health-related quality of life [7,8]. Surgical 4 treatment has been shown to provide better health-related quality of life outcomes than non-surgical treatment, especially in patients with severe deformity [9].…”

mentioning

confidence: 99%

Sagittal alignment changes and postoperative complications after adult spinal deformity surgery in patients with Parkinson’s disease: A multi-institutional retrospective study

Kawabata

Yoshii

Sakai

et al. 2020

Preprint

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Background: Parkinson's disease (PD) has been reported to increase the risk of postoperative complications in patients with adult spinal deformity (ASD). However, those reports are limited, and few have made direct comparisons with patients who do not have PD. Methods:We retrospectively reviewed all surgically treated patients with ASD and at least 2 years of follow-up. Among them, 27 had PD (PD(+) group). Clinical data were collected on early and late postoperative complications and revision surgery. Radiographic parameters were evaluated before and immediately after surgery and at final follow-up, including sagittal vertical axis (SVA), thoracic kyphosis, lumbar lordosis, sacral slope, and pelvic tilt. From the same database, we also retrieved 206 controls without PD (PD(−) group) matched for age, sex, and body mass index.Results: For early complications, the PD(+) group showed a higher rate of delirium than the PD(−) group. Deep vein thrombosis and pulmonary embolism rates tended to be higher in the PD(+) group.For late complications, the rate of pseudarthrosis was significantly higher in the PD(+) group. Rates of rod failure and revision surgery due to mechanical complications also tended to be higher, but not significantly, in the PD(+) group (p = 0.17, p = 0.13, respectively). SVA at final follow-up and loss of correction in SVA were significantly higher in the PD(+) group.Conclusion: Extra attention should be paid to perioperative complications, especially delirium and thrombosis, in PD patients undergoing surgery for ASD. Furthermore, loss of correction and rate of revision surgery due to mechanical complications were higher in these patients. BackgroundParkinson's disease (PD) is a neurodegenerative disorder, the main symptoms of which are rigidity, bradykinesia, and gait disorder. With population aging, the number of patients with this age-related disorder is increasing [1]. In severe cases, PD causes postural disorder, such as anterocollis, Pisa syndrome, and camptocormia [2][3][4][5]. Reports have shown that these postural abnormalities increase susceptibility to rigid spinal deformities [2,3] and that patients with PD develop adult spinal deformity (ASD) more frequently than the general population in the same age groups [6].Recent studies have shown that ASD negatively affects health-related quality of life [7,8]. Surgical 4 treatment has been shown to provide better health-related quality of life outcomes than non-surgical treatment, especially in patients with severe deformity [9]. However, high complication rates have been reported with revision rates of up to 47%. Surgical complications are generally divided into perioperative and late complications. Perioperative complications include epidural hematoma, deep vein thrombosis (DVT), and pulmonary embolism (PE), which are usually seen during or soon after surgery. Late complications, such as junctional kyphosis, rod fracture, and pseudarthrosis, typically occur more than 1 month after surgery and are mainly caused by continuous mechanical stress.Ge...

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A clinical study of the coronal plane deformity in Parkinson disease

Cited by 23 publications

References 35 publications

Evaluation of a computer-aided method for measuring the Cobb angle on chest X-rays

Evaluation of a computer-aided method for measuring the Cobb angle on chest X-rays

Body posture in patients with Parkinson’s disease

Sagittal alignment changes and postoperative complications after adult spinal deformity surgery in patients with Parkinson’s disease: A multi-institutional retrospective study

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