A clinical study of the effects of rocuronium in isoflurane-anaesthetized cats

Prevention of laryngospasm with rocuronium in cats: a dose-finding study

“…The fast onset time and short duration of clinical block documented with rocuronium, both in the current investigation and in previous reports (Auer & Mosing ), make this NMBA a versatile agent, especially if immobility is required for short periods of time. The duration of action in this investigation, even with high doses, was not only short but also showed little variability, suggesting that the time to termination of neuromuscular effects is predictable.…”

Observations on the muscle relaxant rocuronium bromide in the horse – a dose–response study

“…The same dose produced a duration of action in dogs of 20 minutes and in cats of 13 minutes (Adams et al. 2000; Auer & Mosing 2006; Auer 2006).…”

“…In the present study, a dose of 0.6 mg kg )1 of rocuronium produced a 100% blockade with a duration of action (T1 25 ) of 55 minutes. The same dose produced a duration of action in dogs of 20 minutes and in cats of 13 minutes (Adams et al 2000;Auer & Mosing 2006;Auer 2006).…”

Reversal of neuromuscular block in companion animals

“…In general the duration of action of NMBAs (time from administration of the NMBA until T1 = 25% of baseline height) in cats is short. The mean duration of action of rocuronium in cats is 13 minutes (Auer & Mosing 2006). This renders the use of reversal Clutton (2007) agents often unnecessary in this species.The intravenous use of neostigmine (0.4 mg kg À1 ) and edrophonium (0.5 mg kg À1 ) has been reported (Carpenter & Mulroy 1986;Backman et al 1996).…”