A clinical study on pulmonary fistula closure approaches using fibrin adhesives in lung surgery

Tokushima, Takeshi; Fukuta, Mikihisa; Maeta, Hiroyuki; Nisimura, Kengo; Nakai, Kaoru

doi:10.2995/jacsurg.17.559

Cited by 4 publications

(1 citation statement)

References 2 publications

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“…Fibrin glue is often used in combination with covering materials, which works well for intractable air leakages. However, due to the risk of the transmission of infection pathogens, such as the human immunodeficiency virus and human hepatitis virus, it is recommended that fibrin glue be avoided (11,12). In the past decades, pleurodesis provides an excellent effect in preventing postoperative air leakage and recurrence (2,13), however, its disadvantages in diminishing pulmonary function, developing chronic chest pain and negatively affecting future thoracic surgery have made it not a routine intraoperative procedure in some countries, especially for young adults with PSP (14).…”

Section: Discussionmentioning

confidence: 99%

A clinical study of efficacy of polyglycolic acid sleeve after video-assisted thoracoscopic bullectomy for primary spontaneous pneumothorax

Zhang

Miao

et al. 2017

J. Thorac. Dis.

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Section: Discussionmentioning

confidence: 99%

A clinical study of efficacy of polyglycolic acid sleeve after video-assisted thoracoscopic bullectomy for primary spontaneous pneumothorax

Zhang

Miao

et al. 2017

J. Thorac. Dis.

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The short-term efficacy of fibrin glue combined with absorptive sheet material in visceral pleural defect repair

Gika

Kawamura

Izumi

et al. 2006

Interactive CardioVascular and Thoracic Surgery

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Tissue sealants can prevent the occurrence of pulmonary air leakage, although few studies have evaluated the seal-breaking pressure properties of the various methods. We developed a new method for repairing visceral pleural defects which combines fibrin glue with a sheet material. We used an animal model to compare its efficacy with that of three current techniques up to 24 h after application. Under thoracotomy, 5 x 20 mm visceral pleural defects with a depth of 3 mm were made in beagles. The defects in the normal lungs were repaired using 1 of 4 methods: Method A, fibrin-glue double layer (fibrinogen solution was dripped, followed by thrombin solution); Method B, pack method (fibrin glue combined with polyglycolic acid sheet); Method C, rubbing and spray (fibrinogen was rubbed, followed by spraying of both fibrinogen and thrombin solutions); Method D, fibrin-glue-coated collagen fleece. The defects were repaired also in an emphysematous lung model using Method A, B or C. In the normal lungs, Method B showed significantly higher pressure resistance compared with the other methods at 5 min, 1 and 3 h post-application. Pressure resistance increased with time for all methods. In the emphysematous lungs, Method B showed significantly higher seal-breaking pressure than Methods A and C. Compared with existing tissue sealant methods, the pack method reliably controlled pulmonary air leakage immediately after application.

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Clinical study of a new method of closing pulmonary fistula in lung surgery-A combination of PGA felt and frictional spraying of fibrin glue-

Tokushima¹,

Fukuta²,

Maeta³

et al. 2005

Jpn J Chest Surg

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A clinical study on pulmonary fistula closure approaches using fibrin adhesives in lung surgery

Cited by 4 publications

References 2 publications

A clinical study of efficacy of polyglycolic acid sleeve after video-assisted thoracoscopic bullectomy for primary spontaneous pneumothorax

A clinical study of efficacy of polyglycolic acid sleeve after video-assisted thoracoscopic bullectomy for primary spontaneous pneumothorax

The short-term efficacy of fibrin glue combined with absorptive sheet material in visceral pleural defect repair

Clinical study of a new method of closing pulmonary fistula in lung surgery-A combination of PGA felt and frictional spraying of fibrin glue-

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