A clinical trial of the value of recombinant allergen tuberculosis (protein CFP10-ESAT6) in a standard dilution (Diaskintest ®) in the diagnosis of genital tuberculosis in women at risk for disease

Abstract

The study included 154 patients and tested in the examination and treatment FGBU “NIIF St. Petersburg”, Russia's Health Ministry in 2011, in connection with suspected genital tuberculosis. All patients fulfilled clinical and laboratory examination with bacteriological, immunological and histological methods. Comparative analysis revealed that the sensitivity Diaskintest ® exceeds the sensitivity of the Mantoux test with 2 TE (66.7% vs. 55%, respectively), but specificity was lower Diaskintest (75% and 80%, respectively). Consequently, it is advisable to use Diaskintest and Mantoux test with 2 TE complex for early diagnosis of genital tuberculosis, and the correct formation of groups at risk for the development of a specific inflammation of reproductive organs in women who are subject to patient care