A clinico-epidemiological study of childhood herpes zoster

Mitra, Barnali; Chopra, Ajay; Talukdar, Krishna; Saraswat, Neerja; Mitra, Debdeep; Das, Joyjit

doi:10.4103/idoj.idoj_107_18

Cited by 15 publications

(17 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…rate in children below 12 years is only 0.45/1000 persons, whereas in the old age group is 4.5/1000 persons. [1][2][3] The diagnosis of HZ is made mostly on a distinct clinical appearance of vesicles with characteristic dermatomal distribution. Laboratory tests usually are not necessary, but it can be confirmed by a Tzanck smear of vesicles scrapings and viral DNA analysis of the lesion by polymerase chain reaction to differentiate the type of virus.…”

Section: Introductionmentioning

confidence: 99%

“…Relapse of HZ may occur in some immune-compromised patients and most patients respond to treatment with a second course of antiviral treatment which may produce side effects in paediatric patients that demand an alternative treatment approach. 2,5,6 Homoeopathy has vast scope in treatment for HZ lesions like other acute and chronic diseases reducing the length and severity of the illness for restoration of vitality. It holds the potential of improving patients' well-being by ameliorating the debilitating side effects of anti-retro viral drugs.…”

Section: Introductionmentioning

confidence: 99%

“…The age-adjusted incidence rate in children below 12 years is only 0.45/1000 persons, whereas in the old age group is 4.5/1000 persons. 1 2 3…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Homoeopathic Treatment of Childhood Herpes Zoster—A Case Series

2023

View full text Add to dashboard Cite

Background Herpes zoster (HZ) is a relatively rare infectious disease in the paediatric population as compared to adults, occurring due to the reactivation of latent varicella-zoster virus that persists in the posterior root ganglion. HZ can develop any time after the primary infection and is characterised by grouped vesicular rashes limited to single dermatome. Diagnosis is based on a distinct clinical appearance of HZ. Its clinical course is variable, and it requires prompt medical treatment to prevent the complications. In conventional method, antiviral and other treatment modalities are available; however, these are fraught with potentially severe side effects and is expensive that demands an alternative method of treatment. Methods A case series of three children with HZ treated with individualised homeopathy is presented here. The cases are reported according to HOM-CASE guidelines and followed up with photographic documentation. The Modiﬁed Naranjo Criteria for Homeopathy (MONARCH) inventory was used as a tool for assessing the causal relationship between homeopathic intervention and clinical outcome. Results All cases of HZ were successfully cured with individualised homoeopathy within 10 days without any complication. Individual curative response of the homoeopathic medicine in each case was assessed through MONARCH which demonstrated a positive causal attribution of homeopathy. Conclusion Successful results of this case series suggest a positive response of individualised homeopathic medicines in the treatment of childhood HZ. The remissions of the HZ lesion presented in this case series may be attributed to homeopathic medicines in each case. Hence, this case series could serve as a basis for further research into the role of individualised homeopathic medicine in the treatment of childhood herpes zoster.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Homoeopathic Treatment of Childhood Herpes Zoster—A Case Series

2023

View full text Add to dashboard Cite

show abstract

“…Therefore, the presence of HZ in a young child does not always imply the presence of an underlying immunodeficiency or malignancy (3). Although it is predominantly seen in the adult population, the incidence increases in children who have had varicella in utero or in the first 1-2 years of life (1,3,4). Children who have an intrauterine infection are in 18% higher risk of HZ in the first few years of life (1).…”

Section: Introductionmentioning

confidence: 99%

“…Wild-type virus has also been reported to cause HZ in vaccinated healthy children (6). It typically presents as a rash characterized by grouped vesicular skin lesions that are unilateral and dispersed into 1-3 sensory dermatomes, often accompanied by localized pain and/or pruritus on the affected area (1,2,4). Rash in vaccinated children can be severe and occur in the dermatome where the vaccine was injected or at a remote location (9).…”

Section: Introductionmentioning

confidence: 99%

Herpes Zoster in Children; Should the Varicella Vaccine be Administered as a Single Dose or a Double Dose?

Çelik¹,

İnan²

2022

jcp

View full text Add to dashboard Cite

Introduction:In this study, we aimed to evaluate the clinical and epidemiological characteristics of children followed up with the diagnosis of herpes zoster, together with the data of our country. Materials and Methods: Patients who were followed up with the diagnosis of "Herpes Zoster" in the Pediatric Infectious Diseases Clinic of Kayseri Training and Research Hospital between 2016-18 were analysed retrospectively. Results: Twenty (69%) of 29 patients included in the study were female. The mean age of the patients, whose ages ranged from 2 to 16 years, was 8.86±0.6 years. Twenty (69%) of the patients had varicella infection and 6 (20.7%) had a history of single-dose varicella vaccination. The mean age of those who had varicella vaccine was 4.33±0.5, and those who had the varicella infection were 9.9±0.6 years. Four of the patients (13.8%) presented with only rash. Along with the rash, 25 patients (85.8%) had pruritus and 14 (48.3%) described pain. Thoracic dermatomes were most frequently involved with 69%, followed by cervical (17.3%), lumbar (10.3%) and trigeminal (3.4%) dermatomes, respectively. The patients had no known chronic disease, immunodeficiency (primary or secondary) or history of surgical intervention. Conclusion:This study, emphasizes that varicella vaccination can change the epidemiology of HZ in healthy children, causing it to be seen at an earlier age, and emphasizes the importance of two-dose vaccination. ÖzGiriş: Bu çalışmada, herpes zoster tanısı ile takip edilen çocukların klinik ve epidemiyolojik özelliklerini ülkemiz verileri ile birlikte değerlendirmeyi amaçladık. Gereç ve Yöntem: Kayseri Eğitim ve Araştırma Hastanesi, Çocuk Enfeksiyon Hastalıkları Kliniği'nde 2016-18 yılları arasında "Herpes Zoster" tanısı ile takip edilen hastalar retrospektif olarak incelendi. Bulgular: Çalışmaya alınan 29 hastanın 20'si (%69) kızdı. Yaşları 2 ile 16 arasında değişen hastaların yaş ortalaması 8,86±0,6 yıldı. Hastaların 20'sinde (%69) suçiçeği geçirme, 6'sında (%20,7) ise tek doz suçiçeği aşılaması öyküsü vardı. Suçiçeği aşısı olanların ortalama yaşı 4,33±0,5, enfeksiyonu geçirenlerin ise 9,9±0,6 idi. Hastaların 4'ünün (%13,8) başvuru yakınması sadece döküntüydü, 25'inde (%85,8) kaşıntı, 14'ünde de (%48,3) ağrı döküntüye eşlik ediyordu. Torakal dermatomlar en sık (%69) tutulurken, bunu sırasıyla servikal (%17,3),

show abstract

Herpes zoster in outpatient departments of healthcare centers in India: a review of literature

Patki

Vora

Parikh

et al. 2021

Human Vaccines & Immunotherapeutics

View full text Add to dashboard Cite

In India, although incidence of Herpes zoster has not been assessed, regional cases have been reported. We revisited the peer-reviewed literature on clinical cases of HZ to depict the trends in population characteristics, disease presentation, and predisposing factors for the disease in India. Systematically conducted literature search yielded 27 studies, published between January 2011 and May 2020, reporting 3124 HZ clinical cases, with high proportions in older adults (>50 years of age: 15.0-81.3%). Thoracic dermatome was consistently reported as the most frequent site affected by HZ (38.9-71.0%). Postherpetic neuralgia and secondary bacterial infections were the two most frequent complications (10.2-54.7% and 3.5-21.0%, respectively). Despite the paucity of data and gaps in the reporting of HZ cases, available evidence indicate that the disease causes an important burden to older adults in India, suggesting that preventive strategies, along with recommendations to healthcare practitioners, can help mitigate the burden of HZ.

show abstract

A clinico-epidemiological study of childhood herpes zoster

Cited by 15 publications

References 14 publications

Homoeopathic Treatment of Childhood Herpes Zoster—A Case Series

Homoeopathic Treatment of Childhood Herpes Zoster—A Case Series

Herpes Zoster in Children; Should the Varicella Vaccine be Administered as a Single Dose or a Double Dose?

Herpes zoster in outpatient departments of healthcare centers in India: a review of literature

Contact Info

Product

Resources

About