A clinicopathological review of 34 cases of inflammatory breast disease showing an association between corynebacteria infection and granulomatous mastitis

Taylor, Graeme; Paviour, Sue; Musaad, Sahar; Jones, W. O.; Holland, David J.

doi:10.1097/01268031-200335020-00003

Cited by 40 publications

(88 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Other conditions that have been associated with increased risk of IGM include pregnancy, breastfeeding, hyperprolactinaemia with galactorrhoea, and α-1-antitrypsin deficiency 14–17. Infection with Gram-positive bacilli, particularly Corynebacterium kroppenstedtii , has also been reported in a series of cases, but this remains to be elucidated 18. Most of the reported series of IGM have originated in developing countries, and it is postulated that there may be an underdiagnosis of TBM 16 17 19 20.…”

Section: Discussionmentioning

confidence: 99%

Granulomatous mastitis: the histological differentials

Lacambra

Thai²,

Lam³

et al. 2011

J Clin Pathol

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Granulomatous mastitis: the histological differentials

Lacambra

Thai²,

Lam³

et al. 2011

J Clin Pathol

View full text Add to dashboard Cite

show abstract

“…A clinico-pathological review of 34 cases of inflammatory breast disease showing an association between corynobacteria infection and GM showed that 27 of 34 had histological or cytologic features of GM, and gram-positive bacilli were present in the tissue sections of 15 of the women 3. In our case, Gram stains and microbiological cultures did not show any evidence of corynobacteria infection.…”

Section: Discussionmentioning

confidence: 43%

“…Aetiology is still unknown in most patients. Some authors reported an association with autoimmune disorders, infection and trauma,3–5 while others have suggested an association with contraceptive pills, breast feeding, ethnicity and prolactinoma 3–6. The age range at diagnosis ranges from 17 to 42 years 7.…”

Section: Discussionmentioning

confidence: 99%

“…Regarding the infectious aetiology of this disease, there have been some case reports implicating TB mastitis and Corynebacterium spp 3. The most significant differential pathological feature is the presence of caseating necrosis and acid-fast bacilli that can sometimes be isolated in TB cases, although absence of caseating necrosis does not exclude the diagnosis of TB.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Recurrent granulomatous mastitis mimicking inflammatory breast cancer

et al. 2011

View full text Add to dashboard Cite

Granulomatous mastitis (GM) is an uncommon benign breast lesion. Diagnosis is a matter of exclusion from other inflammatory, infectious and granulomatous aetiologies. Here, we presented an atypical GM case, which had clinical and radiologic features overlapping with inflammatory breast cancer (IBC). The disease had multiple recurrences. The patient is a 40-year-old Caucasian woman with a sudden onset of left breast swelling accompanied by diffuse skin redness, especially of the subareolar region and malodorous yellow nipple discharge from the left nipple. The disease progressed on antibiotic treatment and recurred after local resection. A similar lesion developed even after bilateral mastectomy. GM may show clinical/radiologic features suggestive of IBC. Multiple recurrences can be occasionally encountered. GM after recurrence could be much more alarming clinically. Pathology confirmation is the key for accurate diagnosis and a multidisciplinary approach is important to rule out IBC.

show abstract

“…Different combinations of treatments, such as surgery, steroids, antibiotics and methotrexate, have been used with variable efficacy [3][4][5][6][7][8][9][10]. The duration and number of relapses are unpredictable but usually high, and can lead to mastectomies.…”

Section: Introductionmentioning

confidence: 99%