A cloud-based platform for the non-invasive management of coronary artery disease

Sakellarios, Antonis I.; Correia, J.; Kyriakidis, Savvas; Georga, Elena; Tachos, Nikolaos S.; Siogkas, Panagiotis K.; Sans, Francisco; Stofella, Paolo; Massimiliano, Valiani; Clemente, Alberto; Rocchiccioli, Silvia; Pelosi, Gualtiero; Filipović, Nenad; Fotiadis, Dimitrios I.

doi:10.1080/17517575.2020.1746975

Cited by 17 publications

(17 citation statements)

References 22 publications

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“…The XDW standard supports participants in a complex environment to track and manage tasks related to clinical workflows, providing a common interoperability infrastructure to support them. All the documents can be exchanged between organisations through Cross-Enterprise Document Sharing (XDS) repositories, which facilitate the registration, sharing and storage across health enterprises of the patient electronic health records, in order to associate documents containing medical data to a specific workflow [67], [68].…”

Section: Health Information Systems and Standardsmentioning

confidence: 99%

A Cloud Telemedicine Platform Based On Workflow Management System: A Review Of An Italian Case Study

Mitrano¹,

Caforio²,

Calogiuri³

et al. 2022

Adv. sci. technol. eng. syst. j.

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The paper aims to describe a new technological and organizational approach in order to manage teleconsultation and telemonitoring processes involving a Physician, who remotely interacts with one or more Specialists, in order to evaluate and discuss the specific clinical conditions of a patient, based primarily on the sharing of digital clinical data, reports and diagnostic images. In the HINT project (Healthcare INtegration in Telemedicine), a teleconsultation and telemonitoring cloud platform has been developed using a Hub and Spoke architecture, based on a Business Process Management System (BPMS). The specialized clinical centres (Hubs) operate in connection with the territorial hospital centres (Spokes), which receive specific diagnostic consultations and telemonitoring data from the appropriate Specialist, supported by advanced AI systems. The developed platform overcomes the concepts of a traditional and fragmented teleconsultation and consequently the static organization of Hubs and Spokes, evolving towards an integrated clinical workflow management. The project platform adopts international healthcare standards, such as HL7 FHIR, IHE (XDS and XDW) and DICOM for the acquisition and management of healthcare data and diagnostic images. A Workflow Management System implemented in the platform allows to manage multiple and contemporaneous processes through a single platform, correctly associating the tasks to the Physicians responsible for their execution, monitoring the status of the health activities and managing possible clinical issues.

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Section: Health Information Systems and Standardsmentioning

confidence: 99%

A Cloud Telemedicine Platform Based On Workflow Management System: A Review Of An Italian Case Study

Mitrano¹,

Caforio²,

Calogiuri³

et al. 2022

Adv. sci. technol. eng. syst. j.

View full text Add to dashboard Cite

show abstract

“…According to the National Institute for Health and Care Excellence (NICE) guidance on the subject (120), HeartFlow provides an endto-end service that includes anonymization at the source and human intervention (Figures 5,6). Some standalone computational methodology has been proposed for non-invasive calculation of FFR (119,(121)(122)(123)(124). SmartFFR is based on a transient blood flow simulation and the calculation of the pressure-flow curve between the distal and proximal region of the coronary artery.…”

Section: Overview Of Ffr Cta Technologymentioning

confidence: 99%

“…The novelty of SmartFFR lies in the fact that it can be effectively applied on arterial bifurcations and it can be calculated in just a few minutes, without the need of clinical tests besides a good quality CTCA. There is both a cloud-based platform and a standalone version (119,121,122) (Figures 6,7).…”

Section: Overview Of Ffr Cta Technologymentioning

confidence: 99%

Cardiac CT perfusion and FFRCTA: pathophysiological features in ischemic heart disease

Seitun¹,

Clemente²,

Lorenzi³

et al. 2020

Cardiovasc Diagn Ther

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Cardiac computed tomography (CCT) has rapidly evolved, becoming a powerful integrated tool for the evaluation of coronary artery disease (CAD), and being superior to other noninvasive methods due to its high accuracy and ability to simultaneously assess both lumen stenosis and atherosclerotic plaque burden. Furthermore, CCT is regarded as an effective gatekeeper for coronary angiography, and carries independent important prognostic information. In the last decade, the introduction of new functional CCT applications, namely CCT perfusion (CCTP) imaging and CT-derived fractional flow reserve (FFR CTA ), has opened the door for accurate assessment of the haemodynamic significance of stenoses. These new CCT technologies, thus, share the unique advantage of assessing both myocardial ischemia and patient-specific coronary artery anatomy, providing an integrated anatomical/functional analysis. In the present review, starting from the pathophysiology of myocardial ischemia, we evaluate the existing evidence for functional CCT imaging and its value in relation to alternative, well-established, non-invasive imaging modalities and invasive indices of ischemia (currently the gold-standard). The knowledge of clinical applications, benefits, and limitations of these new CCT technologies will allow efficient and optimal use in clinical practice in the near future.

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“…Sakellarios et al used multi-disciplinary human data for the development of predictive models based on machine learning and computational biomechanics demonstrating the efficiency of the platform (73).…”

Section: A B C D Ementioning

confidence: 99%

Technical development in cardiac CT: current standards and future improvements—a narrative review

Toia

Grutta

Sollami

et al. 2020

Cardiovasc Diagn Ther

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Non-invasive depiction of coronary arteries has been a great challenge for imaging specialists since the introduction of computed tomography (CT). Technological development together with improvements in spatial, temporal, and contrast resolution, progressively allowed implementation of the current clinical role of the CT assessment of coronary arteries. Several technological evolutions including hardware and software solutions of CT scanners have been developed to improve spatial and temporal resolution. The main challenges of cardiac computed tomography (CCT) are currently plaque characterization, functional assessment of stenosis and radiation dose reduction. In this review, we will discuss current standards and future improvements in CCT.

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A cloud-based platform for the non-invasive management of coronary artery disease

Cited by 17 publications

References 22 publications

A Cloud Telemedicine Platform Based On Workflow Management System: A Review Of An Italian Case Study

A Cloud Telemedicine Platform Based On Workflow Management System: A Review Of An Italian Case Study

Cardiac CT perfusion and FFRCTA: pathophysiological features in ischemic heart disease

Technical development in cardiac CT: current standards and future improvements—a narrative review

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