A cluster of measles cases in northern Italy: a preliminary report

Filia, Antonietta; Barale, Antonella; Malaspina, Silvana; Montù, Domenico; Zito, Sarah; Muscat, Mark; Atti, M L Ciofi Degli

doi:10.2807/esw.12.48.03318-en

Cited by 5 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite the increase of vaccination coverage and decrease of measles incidence, several outbreaks have occurred in Italy in recent years [8][9][10][11][12], as in other European countries including Romania, Germany, UK and Switzerland [13].…”

mentioning

confidence: 99%

Prevalence of Measles Virus-Specific IgG Antibodies According to Vaccination Schedule in Medical Students of Padua University

et al. 2015

View full text Add to dashboard Cite

aims:The goal of the present study was to establish the efficacy of the measles vaccine and the validity of the vaccination schedule adopted in Italy. Materials & methods: The following procedures are adopted: analyze the compliance to the vaccination schedule; assess the seroprevalence of measles antibodies according to the year of birth and the number of doses; and investigate the persistence of positive antibodies post-vaccination. We gathered and elaborated data of both vaccination history and seroprevalence against measles in a large population of students (4195) belonging to the Medical School of Padua University (Italy). Results: Our results reveal a requirement for a two-dose vaccination schedule to ensure protection from the disease. Nevertheless, these results clearly indicate that the percentage of seropositivity reached using the two-dose strategy is below the percentage (95%) that ensures optimal population immunity. conclusion: It is uncertain whether immune coverage persists when circulating antibodies vanish, but two vaccine doses should prevent disease outbreaks.

show abstract

mentioning

confidence: 99%

Prevalence of Measles Virus-Specific IgG Antibodies According to Vaccination Schedule in Medical Students of Padua University

et al. 2015

View full text Add to dashboard Cite

show abstract

“…The epidemiological analysis indicated the independent introduction of two measles viruses spreading in other epidemic areas, i.e. Piedmont [10, 11] and Germany [21, 22]. In both outbreaks the index case was linked to educational settings where the virus affected a small number of susceptible subjects.…”

Section: Discussionmentioning

confidence: 99%

“…the universal second dose at 5-6 years and a catchup of children attending primary school [5][6][7][8]. Despite these efforts and the considerable decrease of morbidity since 1995, measles is still endemic in Italy and since 2006 a number of outbreaks have occurred in a number of regions, namely Apulia, Lazio and Piedmont ; these outbreaks were caused by two distinct genotypes, D4 and B3 [9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Epidemiological and molecular assessment of a measles outbreak in a highly vaccinated population of northeast Italy

D’Agaro

Molin

Gallo³

et al. 2011

Epidemiol. Infect.

View full text Add to dashboard Cite

Two distinct measles outbreaks, unrelated from the epidemiological point of view but caused by genetically related strains, occurred in the Friuli Venezia Giulia region of northeastern Italy. Forty-two cases were reported during the period April-May 2008. In the first outbreak the index case was a teacher who introduced the virus into the Pordenone area, involving eight adolescents and young adults. The other concomitant outbreak occurred in the city of Trieste with 33 cases. The containment of the epidemics can be explained by the high MMR vaccine coverage in an area where the first dose was delivered to 93·4% and the second dose to 88·3% of the target children. Phylogenetic analysis of 14 measles virus strains showed that they belonged to a unique D4 genotype indistinguishable from the MVs/Enfield.GBR/14.07 strain, probably introduced from areas (i.e. Piedmont and Germany) where this genotype was present or had recently caused a large epidemic.

show abstract

“…This supposition was supported by subsequent epidemiologic investigation that showed that measles was not circulating in this region of Northern Italy before the index case returned from the United Kingdom, and an outbreak occurred subsequent to her return. Example 2 was adapted from the index case in Filia et al 11 Example 3: a healthcare worker develops SARS from an unknown exposure. A healthcare worker developed SARS symptoms on March 28, 2003, with no known occupational exposure to SARS (Figure 3).…”

Section: Individual Investigationsmentioning

confidence: 99%

Identifying the Probable Timing and Setting of Respiratory Virus Infections

Lessler

Brookmeyer

Reich

et al. 2010

Infect. Control Hosp. Epidemiol.

View full text Add to dashboard Cite

show abstract

A cluster of measles cases in northern Italy: a preliminary report

Abstract: From 19 September to 19 November 2007, 46 measles cases related to a single outbreak were reported in the Piemonte region of northern Italy.

Cited by 5 publications

References 0 publications

Prevalence of Measles Virus-Specific IgG Antibodies According to Vaccination Schedule in Medical Students of Padua University

Prevalence of Measles Virus-Specific IgG Antibodies According to Vaccination Schedule in Medical Students of Padua University

Epidemiological and molecular assessment of a measles outbreak in a highly vaccinated population of northeast Italy

Identifying the Probable Timing and Setting of Respiratory Virus Infections

Contact Info

Product

Resources

About