Chem. Sci.
 2024
DOI: 10.1039/d4sc04313h
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A cocktail of Cu2+- and Zn2+-peptoid-based chelators can stop ROS formation for Alzheimer's disease therapy

Anastasia E. Behar,
Galia Maayan

Abstract: The formation of reactive oxygen species (ROS) in the brain can cause neuropathologic degradation associated with Alzheimer's Disease (AD). We report on a cocktail of two chelators that target Cu and Zn and effectively inhibit ROS formation.

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