A Cognitive Occupation-Based programme for people with MS: acceptability, feasibility, and experiences of people with multiple sclerosis

Dwyer, Christopher P.; Oglesby, Megan H.; Joyce, Robert A.; Hynes, Sinéad M.

doi:10.1080/09638288.2023.2239147

Cited by 1 publication

(3 citation statements)

References 42 publications

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“…Fatigue, as measured by the MFIS was the only secondary outcome on which a signi cant effect of the intervention was yielded, with respect to total score, as well as all subscale scores. This nding re ects the positive qualitative reports by participants regarding the fatigue-management elements of COB-MS, as published elsewhere (44). It is also possible that, through fatigue management, participants were able to focus more attention on their goals, with fatigue as a potential barrier, reduced.…”

Section: Discussionsupporting

confidence: 78%

“…Trends in data over time are also presented to indicate the effect of the intervention over time. A qualitative evaluation of the acceptability of the COB-MS and related feasibility has been completed and reported (44).…”

Section: Methodsmentioning

confidence: 99%

“…It is also acknowledged that delivering the COB-MS intervention remotely may have excluded certain groups from being able to participate (those without computer or internet access, those without the requisite computer skills to access the intervention online, etc.) but may have also facilitated the involvement of others (44). This may have limited the diversity of the participants and may have health inequality consequences.…”

Section: Limitationsmentioning

confidence: 99%

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A cluster-randomised controlled feasibility trial evaluating the Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS)

Hynes,

Dwyer,

Alvarez-Iglesias

et al. 2024

Preprint

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Introduction: There is a high prevalence of cognitive difficulties in MS, but despite this, there are few programmes targeting cognition that focus on the ability to function well in everyday life. The Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS), an occupation-focused cognitive intervention, was developed to address this. It focuses on both the functional difficulties and the wide-ranging symptoms that present in MS. Objective: Here we report on the results of a cluster-randomised controlled feasibility trial (ISRCTN11462710; registered 4th September 2019) evaluating the COB-MS in terms of feasibility and initial efficacy as a cognitive intervention for people with MS. Method: Data was collected from people with MS experiencing cognitive difficulties at baseline, post-intervention, 12-weeks, and 6-month follow-up. The primary outcome measure was the Goal Attainment Scaling at 12 weeks. Data was also collected in cognition, quality of life, and mood. Results: One hundred and eighteen people with MS and cognitive difficulties were randomised to either usual care (n=60) or COB-MS intervention (n=58). Ninety-four participants were retained at 6-month follow-up. Those allocated to the COB-MS group had a significant improvement in the primary outcome compared to the control condition. The COB-MS was found to be feasible, including trial procedures and protocol. Data indicates that the COB-MS is accepted by participants and had positive impacts on daily life. Progression criteria have been met. Conclusion: The results provide a strong basis for a pathway to a future definitive trial of COB-MS, with respect to both feasibility and preliminary, clinical efficacy.

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Section: Discussionsupporting

confidence: 78%

Section: Methodsmentioning

confidence: 99%

Section: Limitationsmentioning

confidence: 99%

See 1 more Smart Citation

A cluster-randomised controlled feasibility trial evaluating the Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS)

Hynes,

Dwyer,

Alvarez-Iglesias

et al. 2024

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

A Cognitive Occupation-Based programme for people with MS: acceptability, feasibility, and experiences of people with multiple sclerosis

Cited by 1 publication

References 42 publications

A cluster-randomised controlled feasibility trial evaluating the Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS)

A cluster-randomised controlled feasibility trial evaluating the Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS)

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