A cohort mortality study of leather tanners in Tuscany, Italy

Iaia, Tonina Enza; Bartoli, Dusca; Calzoni, P.; Comba, Pietro; Santis, Marco De; Dini, F; Farina, Giuseppe; Valiani, M.; Pirastu, Roberta

doi:10.1002/ajim.20309

Cited by 15 publications

(14 citation statements)

References 39 publications

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“…Another difference may have been our use of RR estimates from subgroups that are more likely to be highly exposed (eg, exposure duration ≥10 years), although direct comparisons are difficult for the reason given above. We also excluded five studies used by Gatto et al because they were unpublished, involved painters or foundry workers with uncertain exposure,24 25 or overlapped with the already included studies 26 27. However, adding these five excluded studies to our meta-analysis of all studies caused little change (1.27; 95% CI 1.18 to 1.37) since most of these studies only received a small amount of the total weighting.…”

Section: Discussionmentioning

confidence: 99%

Chromium VI and stomach cancer: a meta-analysis of the current epidemiological evidence

et al. 2014

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Section: Discussionmentioning

confidence: 99%

Chromium VI and stomach cancer: a meta-analysis of the current epidemiological evidence

et al. 2014

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“…Co-exposure to other carcinogens, such as silica was discussed by authors with respect to lung cancer SMRs, as was possible confounding by tobacco smoking. Iaia et al [41] reported an SMR of 2.08 (95% CI = 0.05, 11.61) based on one case among Italian leather tanners who were possibly exposed to Cr(VI) in leather pigments. The authors noted that some of the pigments used were lead-based, as well as that co-exposures to numerous other chemicals are prevalent in the tanning industry.…”

Section: Small Intestine Cancermentioning

confidence: 96%

Occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract: A meta-analysis

Gatto

Kelsh

et al. 2010

Cancer Epidemiology

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“…A number of other substances or complex compounds are probable or possible lung carcinogens, for example, welding fumes, lead, vinyl chloride, non arsenical insecticides [1,2]. Elevated lung cancer risks have also been found in several occupations or industries, particularly among painters [2] and, less consistently, in the rubber industry [3], among butchers [4], hairdressers [5], woodworkers [6], leather workers [7] and printers [8,9]. …”

Section: Introductionmentioning

confidence: 99%

Investigation of occupational and environmental causes of respiratory cancers (ICARE): a multicenter, population-based case-control study in France

Luce

Stücker

2011

BMC Public Health

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BackgroundOccupational causes of respiratory cancers need to be further investigated: the role of occupational exposures in the aetiology of head and neck cancers remains largely unknown, and there are still substantial uncertainties for a number of suspected lung carcinogens. The main objective of the study is to examine occupational risk factors for lung and head and neck cancers.Methods/designICARE is a multi-center, population-based case-control study, which included a group of 2926 lung cancer cases, a group of 2415 head and neck cancer cases, and a common control group of 3555 subjects. Incident cases were identified in collaboration with cancer registries, in 10 geographical areas. The control group was a random sample of the population of these areas, with a distribution by sex and age comparable to that of the cases, and a distribution by socioeconomic status comparable to that of the population. Subjects were interviewed face to face, using a standardized questionnaire collecting particularly information on tobacco and alcohol consumption, residential history and a detailed description of occupational history. Biological samples were also collected from study subjects. The main occupational exposures of interest are asbestos, man-made mineral fibers, formaldehyde, polycyclic aromatic hydrocarbons, chromium and nickel compounds, arsenic, wood dust, textile dust, solvents, strong acids, cutting fluids, silica, diesel fumes, welding fumes. The complete list of exposures of interest includes more than 60 substances. Occupational exposure assessment will use several complementary methods: case-by-case evaluation of exposure by experts; development and use of algorithms to assess exposure from the questionnaires; application of job-exposure matrices.DiscussionThe large number of subjects should allow to uncover exposures associated with moderate increase in risks, and to evaluate risks associated with infrequent or widely dispersed exposures. It will be possible to study joint effects of exposure to different occupational risk factors, to examine the interactions between occupational exposures, tobacco smoking, alcohol drinking, and genetic risk factors, and to estimate the proportion of respiratory cancers attributable to occupational exposures in France. In addition, information on many non-occupational risk factors is available, and the study will provide an excellent framework for numerous studies in various fields.

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A cohort mortality study of leather tanners in Tuscany, Italy

Cited by 15 publications

References 39 publications

Chromium VI and stomach cancer: a meta-analysis of the current epidemiological evidence

Chromium VI and stomach cancer: a meta-analysis of the current epidemiological evidence

Occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract: A meta-analysis

Investigation of occupational and environmental causes of respiratory cancers (ICARE): a multicenter, population-based case-control study in France

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