A cohort study of chronic diseases for Mongolian people: Outline with baseline data of the Moncohort study

Enkh-Oyun, Tsogzolbaatar; Davaalkham, Dambadarjaa; Kotani, Kazuhiko; Aoyama, Yasuko; Tsuboi, Satoshi; Ae, Ryusuke; Gombojav, Davaa; Dayan, Angarmurun; Nanjid, Khuderchuluun; Nakamura, Yosikazu

doi:10.1016/j.jegh.2015.12.001

Cited by 5 publications

(3 citation statements)

References 22 publications

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“…While contingent on efforts to increase the diversity and quality of foods supplied, one important strategy that will improve both micronutrient intake and NCD risk in Mongolia will be the revision of the country's dietary guidelines, which are both inadequately publicized and are not well-informed by nutrition science [53]. Finally, research priorities going forward should include the compilation, dissemination, and periodic update of national food composition data as many unique local dairy products and other foods cannot be easily imputed using foreign data; development, validation, and dissemination of standardized dietary assessment instruments; implementation of a national dietary surveillance system (potentially co-opting available household and commercial data platforms [54]); and continued development and follow-up of cohorts and other study populations for the purpose of nutritional epidemiology [55].…”

Section: Discussionmentioning

confidence: 99%

Diet and Nutrition Status of Mongolian Adults

Bromage

Tselmen²,

Lander

et al. 2020

Nutrients

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(1) Background: Aspects of the Mongolian food supply, including high availability of animal-source foods and few plant foods, are plausibly associated with disease in the population. Data on Mongolian diets are lacking, and these risks are poorly quantified. The purpose of this study was to provide a multifaceted nutritional analysis of the modern Mongolian diet. (2) Methods: The study population consisted of 167 male and 167 female healthy non-pregnant urban and nomadic adults (22–55 years) randomly selected from lists of residents in 8 regions. From 2011–2016, 3-day weighed diet records and serum were collected twice from each participant in summer and winter; anthropometry was collected once from each participant. Serum was analyzed for biomarkers, and nutrient intake computed using purpose-built food composition data and adjusted for within-person variation. Exploratory dietary patterns were derived and analyzed for associations with diet and nutrition measurements. (3) Results: We collected 1838 of an expected 1986 diet records (92.5%), 610/658 serum samples (92.7%), and 315/334 height and weight measurements (94.3%). Sixty-one percent of men and 51% of women were overweight or obese. Consumption of red meat, refined grains, and whole-fat dairy was high, while that of fruits, non-tuberous vegetables, eggs, nuts and seeds, fish and poultry, and whole grains was low. Dairy and red meat were more consumed in summer and winter, respectively. Dietary inadequacy of 10 of 21 assessed nutrients, including fiber, folate, and vitamin D were >50% prevalent, while protein, zinc, and vitamin B12 inadequacy were low. Biochemical evidence of iron and vitamin A deficiency was also low. Three dietary patterns (Urban, Transitional, Nomadic) explained 41% of variation in food consumption. The Urban pattern was positively associated with BMI in multivariate analysis. (4) Conclusions: Results indicate a high prevalence of key dietary inadequacies and overweight among Mongolian adults. Prior studies by our group have suggested that expanded supplementation and food fortification would be effective in addressing micronutrient inadequacies; these strategies should be coupled with measures to mitigate the growing burden of chronic disease.

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Section: Discussionmentioning

confidence: 99%

Diet and Nutrition Status of Mongolian Adults

Bromage

Tselmen²,

Lander

et al. 2020

Nutrients

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“…The health burden of non-communicable diseases such as cardiovascular illness and diabetes mellitus has increased year by year in Mongolia and is thus becoming a leading cause of kidney disease. Large cross-sectional studies conducted in six regions of the world revealed that hypertension, diabetes, obesity, and high cholesterol level were all independently associated with chronic kidney disease, and the prevalence of chronic kidney disease was 18.0% (15.5-20.8%) in Mongolia [8][9][10][11][12] .…”

Section: Introductionmentioning

confidence: 99%

“…Although there are some research studies on the prevalence of renal diseases and its risk factors in Mongolia, we are aware of only one single study on the use of potentially inappropriate drugs in the elderly [7][8][9][10][11][12] . We are unable to identify other peerreviewed studies on the use of potentially inappropriate drugs in elderly Mongolian patients with kidney disease.…”

Section: Introductionmentioning

confidence: 99%

Potentially Inappropriate Medications in Hospitalized Elderly Patients with Kidney Disease

Batsukh

Ganbold

Olonbayar

et al. 2019

Cent. Asian j. Med. Sci.

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Objective: Our purpose was to use the Beers criteria to determine potentially inappropriate medications in people 65 years of age and older who were hospitalized in the Nephrology and Endocrinology Department of The Second General Hospital in Ulaanbaatar, Mongolia from October to December in 2017. Methods: A total of 75 patients' medical records were selected who were aged ≥ 65 and diagnosed with kidney diseases. The patient's age, sex, serum creatinine, the number of potentially inappropriate medications prescribed were determined. Descriptive statistics, frequency analysis, and t-tests were used for normally distributed variables. The Mann-Whitney U test was used for variables with a non-normal distribution. Results: Most patients for whom data were creatine clearance data were available (36/41, 87%) were prescribed at least one potentially inappropriate medication, and the number prescribed of potentially inappropriate medications was moderately correlated with length of hospital stay (r= .326, p < .05). The frequency of potentially inappropriate medications prescribed in patients with CrCL <60 ml/min was significantly higher than in patients with CrCL level 60 -90 ml/min (29/31 vs. 7/10, X 2 (1) = 50.45, p < .001). A total of 195 potentially inappropriate medications were prescribed to 75 elderly patients diagnosed with renal disease, and these included antibiotics, anticonvulsants, proton pump inhibitors, and calcium channel blockers. Conclusion: Potentially inappropriate medications were frequently prescribed to hospitalized geriatric patients with kidney disease. Health care professionals in Mongolia need to collaborate to optimize pharmacotherapy based on renal function to avoid the complications of potentially inappropriate medications for geriatric patients with kidney disease.

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