A collaborative robotic platform for sensor-aware fibula osteotomies in mandibular reconstruction surgery

Hu, Junlei; Liu, Jiannan; Guo, Yan; Cao, Zhenggang; Chen, Xiaojun; Zhang, Chenping

doi:10.1016/j.compbiomed.2023.107040

Cited by 2 publications

(1 citation statement)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Surgery is the primary treatment modality for HNSCC [3,[10][11][12], while radiotherapy and chemotherapy are the main treatment options for inoperable cases, advanced-stage disease, or recurrent cases [13][14][15][16]. Digital techniques, navigation surgery, and artificial intelligence have been integrated into the overall management of HNCs, further enhancing the precision, safety, and effectiveness of treatment plans [17][18][19].…”

Section: Introductionmentioning

confidence: 99%

Clinical Advances and Future Directions of Oncolytic Virotherapy for Head and Neck Cancer

Wang,

Sun,

et al. 2023

Cancers

View full text Add to dashboard Cite

Oncolytic viruses (OVs), without harming normal tissues, selectively infect and replicate within tumor cells, to release immune molecules and tumor antigens, achieving immune-mediated destruction of tumors and making them one of the most promising immunotherapies for cancer. Many clinical studies have demonstrated that OVs can provide clinical benefits for patients with different types of tumors, at various stages, including metastatic and previously untreatable cases. When OVs are used in combination with chemotherapy, radiotherapy, immunotherapy, and other treatments, they can synergistically enhance the therapeutic effects. The concept of oncolytic virotherapy (OVT) was proposed in the early 20th century. With advancements in genetic engineering, genetically modified viruses can further enhance the efficacy of cancer immunotherapy. In recent years, global research on OV treatment of malignant tumors has increased dramatically. This article comprehensively reviews the findings from relevant research and clinical trials, providing an overview of the development of OVT and its application in the clinical treatment of head and neck cancer. The aim is to offer insights for future clinical and fundamental research on OVT.

show abstract