The hydraulic fracturing technique (also termed mini-frac test) is commonly used to estimate the in situ stress field. We recently conducted a mini-frac stress measurement campaign in the newly-established Bedretto Underground Laboratory (BedrettoLab) in the Swiss Alps. Four vertical boreholes, dedicated for stress characterization of the granitic rock mass, hosted a total of 19 mini-frac test intervals. Systematic pressure transient analysis was performed to carefully estimate the magnitude of the least principal stress ($$S_\mathrm {3}$$
S
3
). We compared five different methods (inflection point, bilinear pressure decay rate, tangent, fracture compliance, and jacking pressure) to identify an adequate approach best suited for our test scale and the host rock mass. We found that the methods used to determine the fracture closure pressure underestimate the magnitude of $$S_\mathrm {3}$$
S
3
, presumably due to the rapid closure of the hydraulic fracture after shut-in. The most consistent results were found using the inflection point and bilinear pressure decay rate method, which both determine the (instantaneous) shut-in pressure as the proxy for the $$S_\mathrm {3}$$
S
3
magnitude. The determined shut-in pressure, or $$S_\mathrm {3}$$
S
3
magnitude, is $$14.6\pm 1.4$$
14.6
±
1.4
MPa from the inflection point method. This allowed us to further estimate the stress environment around the BedrettoLab, which is transitional between normal and strike-slip faulting. The measured local pore pressures from extended shut-in periods are between 2.0 and 5.6 MPa, significantly below hydrostatic. A combination of drainage, cooling, and the excavation damage zone of the tunnel may have significantly perturbed the in situ stress field in the vicinity of the BedrettoLab.