A color-tunable single-benzene fluorophore-based sensor for sensitive detection of palladium in solution and living cells

Abstract

Single- benzene fluorophores are bright and the smallest fluorochromes known so far. In single-benzene fluorophores, the fluorescence is mediated by push/pull effect of substituting groups. Despite a plethora of advantageous...

meta-Fluorophores: an uncharted ocean of opportunities

“…61 The next group of molecules in this series contains the -CN group as the A moiety and different acyclic and cyclic -N-alkyl groups as the D moiety (Chart 4). 44,[65][66][67] This group of molecules through structural variation emits a wide colour gamut, ranging from blue to red, both in solution as well as in the solid state. Moreover, some of these molecules (Chart 4, molecules 20j, 21a, 21d, 22a, 22b) exhibit two-photon solid-state emission.…”

Green Fluorescent Diamino‐Terephthalonitriles with Reactive Terminal Groups Towards Synthesis of Value‐Added Fluorophores

“…Am‐TN‐SBFs have amines as the donor moiety and nitrile as the acceptor unit placed ortho to each other on the benzene ring. We and other groups have developed various highly emissive Am‐TN‐SBFs [19–24] . Strong fluorescence behavior is seen when there is good degree of planarization between the electron‐donating amine and electron‐accepting para‐ benzodinitrile units in the ground state and excited state geometries.…”

“…Am‐TN‐SBFs are constructed through a facile nucleophilic aromatic substitution reaction (S N Ar) on tetrafluoroterephthalonitrile (TFTN), to replace one or two fluorines with electron‐rich amines [19–24] . Substitution of the remaining fluorines is comparatively harder due to the increased electron richness of the SBF moiety [22,26a,b] .…”

“…Am-TN-SBFs are constructed through a facile nucleophilic aromatic substitution reaction (S N Ar) on tetrafluoroterephthalonitrile (TFTN), to replace one or two fluorines with electron-rich amines. [19][20][21][22][23][24] Substitution of the remaining fluorines is comparatively harder due to the increased electron richness of the SBF moiety. [22,26a,b] The overall polarity and sterics of first amine on the SBF directs the regioselectivity of the reaction towards ortho or para di-substitution.…”

Aggregation-Induced Modulation of Ground and Excited State Photophysics of 5-(tert-Butyl)-2-Hydroxy-1,3-Isophthalaldehyde (5-tBHI)

“…Organic emitters, based on a single benzene scaffold, have been explored extensively because of their trouble-free syntheses, low cost, and unique photophysical properties like solid-state emission, high quantum yield, and specific wave guidance for optoelectrical applications. − Commonly, tunable emission is the key factor since it empowers the performance of the emitter in optoelectronic applications by easily modulating the molecular composition, phase, and packing arrangements. However, the development of a single benzene-based emitter (SBBE), which could have color-tunable emission responses against external factors like optical output, temperature, pressure, electrical current, etc., is still challenging, as evident from only a few reported studies .…”