2023
DOI: 10.3389/fcvm.2023.1224462
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A combination of strongly associated prothrombotic single nucleotide polymorphisms could efficiently predict venous thrombosis risk

Shewaye Fituma Natae,
Mohammed Abdulridha Merzah,
János Sándor
et al.

Abstract: BackgroundVenous thrombosis (VT) is multifactorial trait that contributes to the global burden of cardiovascular diseases. Although abundant single nucleotide polymorphisms (SNPs) provoke the susceptibility of an individual to VT, research has found that the five most strongly associated SNPs, namely, rs6025 (F5 Leiden), rs2066865 (FGG), rs2036914 (F11), rs8176719 (ABO), and rs1799963 (F2), play the greatest role. Association and risk prediction models are rarely established by using merely the five strongly a… Show more

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