“…The distribution of can be substantially different from that of : the score based on the true nuisance parameters. Indeed, under the null hypothesis, the asymptotic variance of is not the Fisher information, but the effective Fisher information (Rippon and Rayner (), Rayner (), Hall and Mathiason (), Marohn () and Cox and Hinkley (), section 9.3), which is also the asymptotic variance of the effective score , which is defined below. The effective information is smaller than the information, given that the score for the parameter of interest and the nuisance score are correlated.…”